INTRODUCTION Congenital abnormalities of the inner ear is the most common cause of neurosensory hearing loss. Michel inner ear deformity is a rare developmental anomaly refers to the total aplasia of the inner ear. It is caused by developmental arrest of otic placode early during the third week of gestational age. CASE REPORT We have discussed here that three year old girl diagnosed Michel ap...

BACKGROUND Congenital cytomegalovirus (CMV) infection is a leading cause of sensorineural hearing loss (SNHL). The mechanisms of pathogenesis of CMV-related SNHL are still unclear. The aim is to study congenital CMV-related damage in the fetal inner ear, in order to better understand the underlying pathophysiology behind CMV-SNHL. RESULTS We studied inner ears and brains of 20 human fetuses, ...

(Edmonds C. Inner ear barotrauma: a retrospective clinical series of 50 cases. SPUMS J. 2004; 34: 11-4.) A retrospective series of 50 cases of inner ear barotrauma is reviewed, as regards the diving and otological history, the clinical manifestations, basic audiometric investigations and treatments. This disorder may be predicted to some degree by a previous history of otological barotraumas, o...

The elongation and contraction of outer hair cells (OHCs) greatly contribute to the high sensitivity and frequency selectivity of the mammalian inner ear. The motility of OHCs is believed to be based on the conformational changes of the motor protein prestin in the plasma membrane of OHCs. In the present study, four lines of research on the inner ear were conducted. First, the mechanism by whic...

Autoimmunity is thought to be one cause of sensorineural hearing loss (SNHL). Sera from patients with rapidly progressive hearing loss have been shown to contain antibodies to a 68-kD protein in heterologous inner-ear tissue. Using guinea pig inner-ear tissue as the antigenic substrate and either Western blot or immunofluorescence (IF) or both, we tested sera from 74 patients suspected to have ...

Cutaneous skin tags are common skin growths, usually harmless, which protrude from the skin and may have a short, narrow stalk. Typically, they are the same color as the skin or a little darkerand appear mostly in the axilla, groin, and cervical area. In this report, we present a 30-year-old female with pedunculated and <spa...

In accordance with longstanding convention, the adult ear is here described in terms of its three portions, namely the outer, the middle and the inner ear. The inner ear, comprising the bony and membranous labyrinth with its central connections, arises from a set of structures quite distinct from those which give rise to the outer and middle ears. The development of the inner ear, which is the ...

In vertebrates, the inner ear arises from the otic placode, a thickened swathe of ectoderm that invaginates to form the otic vesicle. We report that histone demethylase KDM4B is dynamically expressed during early stages of chick inner ear formation. A loss of KDM4B results in defective invagination and striking morphological changes in the otic epithelium, characterized by abnormal localization...

In this review the authors discuss the physiopathologic and electrophysiologic changes of the inner ear in Meniere's disease, otosclerosis, ototoxicity, acoustic neuroma, presbycusis, noise-induced hearing loss, metabolic hearing loss, perilymphatic fistula, syphilis, autoimmune inner ear disease, congenital genetic hearing loss, and viral labyrinthitis. The etiology and pathogenesis of hearing...

Arteriovenous malformations are rare in the head and neck region and generally arise from intracranial vessels. We present two rare cases with spontaneous arteriovenous malformations related to the ear. The role of magnetic resonance imaging and colour Doppler sonography in the diagnosis and management of such cases is discussed along with a review of the literature.