Deficits in attentional-inhibitory control have been reported to correlate to anger, hostility, and aggressive behavior; therefore, inhibitory control appears to play an important role in prosocial behavior. Moreover, recent studies have demonstrated that oxytocin (OT) exerts a prosocial effect (e.g., decreasing negative behaviors, such as aggression) on humans. However, it is unknown whether t...

BACKGROUND In previous studies, the relaxant, anticholinergic (functional antagonism) and antihistaminic effects of Nigella sativa have been demonstrated on guinea pig tracheal chains. To elucidate the other mechanisms responsible for the relaxant effect of this plant, its inhibitory effect on the calcium channel was examined in this study. RESULTS The inhibitory effects of both concentration...

background many studies have shown that h2s protects the gastric mucosa on different models of stress but till now there are few studies about the effects of h2s on gastric acid secretion. therefore, the aim of the present study was to investigate the role of autonomic nervous system in mediating the inhibitory effect of hydrogen sulfide donor (nahs) on stimulated gastric acid secretion in rats...

Nepeta glomerulosa Boiss. is a medicinal plant has been used in traditional medicine. The aim of this study was to evaluate the anti-melanogenesis inhibitory activity of MeOH, n-hexane, ethyl Acetate (EtAc), dichloromethane (CH2Cl2), n-butanol (BuOH) and H2O extracts isolated from N. glomerulosa in B16 melanoma cell line. The B16F10 cell line viability after treatment with increasing concentrat...

the role of opioid receptor and voltage dependent calcium channels on the kindling induced by the convulsant pentylenetetrazole (ptz) were investigated in the rats. experiment involved 24 rats which were divided into four groups. kindling was established with ptz in subconvulsive dose (37.5 mg/kg i.p.) every 48 h and effects were observed within 20 min using five-point scoring system. all anima...

Background: Teucrium polium is a medicinal plant used as an herbal plant for antispasmodic and antimicrobial properties. Objective: This study aimed to evaluate the effect of the essential oil of T. polium against fungal, bacterial strains, and Giardia lamblia. Also, chemical analysis of the essential oil of T. polium was analyzed by GC/MS. Methods: Teucrium polium was collected from the De...

Ketotifen is a benzocycloheptathiophene with a range of pharmacological activities. The present study was carried out to evaluate the action of ketotifen on isolated rat bladder contractions induced by KCI and acetylcholine, compared with the effects of other drugs. Ketotifen (5 µM) reduced the response to acetylcholine on rat isolated bladder without altering the maximum response and shift...