To the Editor: There have been a number of questions concerning the validity of regional cerebral blood flow from the brain stem and cerebellar regions recorded after inhalation of 133 Xe after placement of probes in the suboccipital region (see p. 203). These posterior fossa measurements have been a relatively new contribution from this laboratory and their validity may be questioned since det...

BACKGROUND The optimal ventilated status under total intravenous or inhalation anesthesia in neurosurgical patients with a supratentorial tumor has not been ascertained. The purpose of this study was to intraoperatively compare the effects of moderate hyperventilation on the jugular bulb oxygen saturation (SjO 2 ), cerebral oxygen extraction ratio (O 2 ER), mean arterial blood pressure (MAP), a...

After incubation with DNA human lymphocytes release neutral and acid DNase activities into the culture medium; the release depends on DNA concentration and time of cultivation. The electrophoretic mobility of the released neutral DNase activity is in accordance with DNase I and the electrophoretic mobility of the released acid DNase activity with DNase II. The released DNase activities do not o...

Total intravenous anaesthesia (TIVA) is defined as a technique of general anaesthesia using a combination of agents given solely by the intravenous route and in the absence of inhalational agents. This article reviews the indications, advantages and disadvantages, principle, mode of administration, clinical techniques and drugs used for TIVA. Total intravenous anesthesia, or TIVA, can provide a...

We report a very rare case of Sevoflurane Induced Diffuse Alveolar Hemorrhage in a previously healthy young adult in the post-operative period following general anesthesia. Diffuse alveolar hemorrhage (DAH) associated with inhalation injury from halogenated gases is a unique entity in the literature that practicing clinicians should be cognizant of and considered in post-operative cases of acut...