the leukotrienes and prostaglandins are biologically active metabolites derived from arachidonic acid. the leukotrienes have a role in inflammatory diseases such as allergic rhinitis, inflammatory bowel disease and asthma. montelukast, a cysteinyl leukotriene receptor antagonist, is claimed to be effective in asthma. the present study aimed to assess the role of cysteinyl leukotriene receptor a...

Inflammatory pseudotumor of the liver is a focal mass consisting proliferation of plasma cells and other inflammatory cells. This rare disease should be . included in differential diagnosis in patients with hepatic mass in imaging studies, which to avoid surgery. Case Report. A 49 years old woman admitted in Shohada Hospital with epigastric pain the imaging studies was done (U.S.-C. T). Two S...

Marine saponins are naturally glycosides compounds which possess important biomedical properties such as anti-cancer, antioxidant and anti-inflammatory. Nevertheless, no systematic studies on the anti-inflammatory potential of brittle star saponin and its underlying mechanisms have been reported. In this study, Ophiocoma erinaceus extracted saponin was investigated for its in vitro anti-inflamm...

neovascularization of the normally avascular cornea was associated with a notable increase in the expression of the major pro-angiogenic factors, inflammatory cytokines and proteases. the data supporting a causal role for vascular endothelial growth factor (vegf), inflammatory cytokines and matrix metalloproteinase (mmps) are extensive. anti-angiogenic/anti-inflammatory therapy is considered as...

Objective(s) In recent years highly selective COX-2inhibitors were withdrawn from the market because of an increased risk of cardiovascular complications. In this study we were looking for potent compounds with moderate selectivity for cox-2. So, four analogues of 4, 5-diaryl-2-(2-alkylthio-5-imidazolyl) imidazole derivatives were synthesized and their anti-inflammatory and anti-nociceptive ac...

background although, melasma is most prevalent among asian young women, and also darkly pigmented individuals are particularly prone to developing post inflammatory hyperpigmentation, to the best of our knowledge, there are rare or no studies about the association of melasma and post inflammatory hyperpigmentation. results we found out that 24.1% of patients without melasma had post-acne pigmen...