BACKGROUND A prospective study of infectious encephalitis was conducted in France in 2007. In total, 253 patients were enrolled with a proven etiological diagnosis for 52%. The cohort of surviving patients with encephalitis was assessed for sequelae and impairment 3 years after enrollment. METHODS Patients, their family, and general practitioners (GPs) were interviewed by phone to document pe...

There are few conditions more devastating than severe encephalitis, in which a previously healthy child progresses, within days, from a nonspecific and apparently benign febrile illness to coma, seizure and irreversible brain injury. The current article focuses on key aspects of the etiology and management of acute and subacute childhood encephalitis beyond the neonatal period in the Canadian c...

PURPOSE We aimed to study whether ketogenic diet (KD) therapy leads to resolution of super-refractory status epilepticus in pediatric patients without significant harm. METHOD A retrospective review was performed at Phoenix Children's Hospital on patients with super-refractory status epilepticus undergoing ketogenic diet therapy from 2011 to 2015. RESULTS Ten children with super-refractory ...

the histopathological findings include as following: gliosis (52%), neuronal necrosis (37%), perivascular cuffing (5.4%), hyperemia and hemorrhage in cerebral tissues (32.9%), hyperemia and hemorrhage in meninge(19.2%), prevascullar and preneuronal edema (52%), meningial edema (16.4%), vacuole in neurons (2.7%), vacuoleinneuropil( 8.2% ),protozoal cyct(5.4%). frequency of fetal brain lesions co...

An encephalitic illness with a fatal outcome occurred in a 9 month old girl with virologically confirmed exanthem subitum. Human herpes-virus-6 (HHV-6) DNA was found in the cerebrospinal fluid at the acute stage of the disease by the polymerase chain reaction, but the virus antigen was not detected in her brain tissue. This suggests that HHV-6-induced encephalitis/encephalopathy may be due to a...

Here we report the case of Mrs. O., a 57 years-old woman presenting with mood disorder with psychotic symptoms developing strange skin lesions, ultimately leading to the suspected diagnosis of varicella-zoster encephalitis. The later appearance of a post-infectious acute inflammatory demyelinating polyradiculoneuropathy further confirmed the suspect. This case stresses the importance for not di...

Anthropogenic landscape changes contributed to the reduction of availability of habitats to wild animals. Hence, the presence of wild terrestrial carnivores in urban and peri-urban sites has increased considerably over the years implying an increased risk of interspecies spillover of infectious diseases and the transmission of zoonoses. The present study provides a detailed characterisation of ...

Encephalitis, an infectious or inflammatory process in the brain tissue, mainly caused by a virus, is a disease of children and young adults but may appear at any age. The picture has been changing along with vaccination and new emerging viruses, and along with therapeutic regimens, especially immunosuppression. Conventional childhood viruses, measles, mumps and rubella (MMR), are replaced by W...