Infectious bronchitis virus (IBV) is an acute and contagious viral disease of poultry that affects different systems, including the respiratory tract in particular. IBV causes major economic losses in the poultry industry globally. Due to antigenic variation of the causative agent, control of the disease is difficult. To control the disease, many vaccines that belong to different serotypes are...

In this experimental study, our objective was to investigate the macroscopic, microscopic and immunohistochemical findings developed in respiratory system due co-infection with infectious bronchitis virus (IBV) M-41 commensal Bordetella avium tract 15-day-old female Brown-Nick chicks. a total of 70 non-SPF, healthy chicks were randomized into 4 groups. The Group 1 (n=20) infected only IBV-M41 s...

Infectious bronchitis virus (IBV) causes respiratory disease leading to loss of egg and meat production in chickens. Although it is known that macrophage numbers are elevated in the respiratory tract of IBV infected chickens, the role played by macrophages in IBV infection, particularly as a target cell for viral replication, is unknown. In this study, first, we investigated the ability of IBV ...

in order to identify predominant circulating types of infectious bronchitis(ib) virus in the period of 1999-2004 in iran, samples(trachea, lung, kidney) from 150 various flocks showing respiratory signs suspected to be related to ib infection were inoculated to spf eggs. then allantoic fluids studied by rt-pcr and nested pcr using group and type specific primers to probing massachusset, 793/b a...

This study describes the isolation, serotyping and genotyping of 54 infectious bronchitis virus (IBV) cases predominantly in KwaZulu-Natal and compared to several isolates from other South African provinces between 2011 and 2012 and several historic isolates. The results indicate the division of isolates into two different genotypes of IBV within the province, Massachusetts (Mass)-like and QX-l...

In eukaryotic cells, cell growth and division occur in a stepwise, orderly fashion described by a process known as the cell cycle. The relationship between positive-strand RNA viruses and the cell cycle and the concomitant effects on virus replication are not clearly understood. We have shown that infection of asynchronously replicating and synchronized replicating cells with the avian coronavi...

this experimental study was carried out to induce a co-infection of h9 aiv and ibv with inoculumsprepared from tracheal scrubbed epithelium tissues in natural co-infected birds to rule out the effect of fieldundesired environmental conditions and also other infectious causative agents. eighty 1-day-old broilerswere randomly divided into four equal groups. at 21 days of age, three test groups we...

infectious bronchitis virus (ibv) is a contagious pathogen in fowl that results in economic loss in the poultry industry. in this study, the amino acids sequences of three structural proteins m, n, and s1 for five iranian ibv isolated during 1998-2011 have been analyzed. conserved and variable regions, hydrophobic characteristics and identity matrix were determined after alignment by bioedit ve...

Avian infectious bronchitis (IB) is a major cause of economic losses in poultry industry. The IB virus primarily affects respiratory tract, but various strains differ in their tropism for other target organs such as kidney and alimentary tract. The objective of this study was to estimate the pathogenicity of Iranian IBV variant (IR-1), which is limited exclusively to Iran. Specific pathogen fre...

All coronaviruses possess small open reading frames (ORFs) between structural genes that have been hypothesized to play important roles in pathogenesis. Infectious bronchitis virus (IBV) ORF 3a is one such gene. It is highly conserved among group 3 coronaviruses, suggesting that it has an important function in infection. IBV 3a protein is expressed in infected cells but is not detected in virio...