Wound Healing Skin disorders or injuries can weaken its barrier function, making a wound vulnerable to bacterial infection. Bacteria secrete proteases that disrupt the integrity, delaying healing. In article 2202472, Robert Deller, Man Li, Rachel Williams, Raechelle D'Sa, and colleagues describe potential of nitric oxide-releasing peptide hydrogels prevent loss function from secreted in order i...

surgical wound infections are usually encountered due to the endogenous rather than the exogenousinfective sources. the objective of this study was to evaluate the effect of a distant inoculated infective source on the contamination of surgical wounds. thirty white new zealand rabbits divided randomly into three control and three treatment equal groups. in treatment groups 24 hrs before surgica...

UNLABELLED Cavus foot surgeries are relatively common procedures in pediatric orthopedics. Following surgery, the tensile forces exerted on the wound by the newly corrected foot may hinder soft tissue healing and lead to wound dehiscence. Treatments including skin grafting and other plastic surgery procedures have been described in order to manage this complication. However, the effectiveness o...

Post operative wound infection is considered as a surgeon’s nightmare. Before the mid 19 century, surgical patients commonly developed post operative purulent discharge from their incisions, followed by overwhelming sepsis, and often death. It was not until the late 1860s, after Joseph Lister introduced the principles of antisepsis that postoperative infections morbidity decreased substantially...

Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that removes exudates and other potentially infectious material, protects the surg...

BACKGROUND Delayed primary closure in cases of acute appendicitis is debated among the surgeons as to whether it decreases the rate of wound infection in comparison to primary closure. The aim of this study was to find out the optimal method of wound closure in cases of perforated appendicitis. METHODS This randomized control trial was conducted at the surgical units of Ayub Teaching Hospital...