Mechanical forces play critical roles in the function of living cells. However, the underlying mechanisms of how forces influence nuclear events remain elusive. Here, we show that chromatin deformation as well as force-induced transcription of a green fluorescent protein (GFP)-tagged bacterial-chromosome dihydrofolate reductase (DHFR) transgene can be visualized in a living cell by using three-...

OBJECTIVES The aim of this study was to evaluate the effects of damping on stress concentration in an impacted incisor. METHODS Damping ratios of maxillary incisors were tested using an in vivo modal testing method. A finite element model of the upper central incisor was established for dental trauma analysis. To assess the effect of damping properties on induced stresses in the traumatized i...

In nature, plants are exposed to biotic and abiotic stresses that often occur simultaneously. Therefore, plant responses to combinations of stresses are most representative of how plants respond to stresses. We used RNAseq to assess temporal changes in the transcriptome of Arabidopsis thaliana to herbivory by Pieris rapae caterpillars, either alone or in combination with prior exposure to droug...

[1] The tectonic evolution of Mars has been driven primarily by the interaction of Tharsisinduced loading stresses with a uniform contractional stress field, leading to global assemblages of graben and wrinkle ridges. Until recently, strike-slip faults have appeared to be largely absent from the tectonic record. We here present evidence for a new set of Noachian to Early Hesperian strike-slip f...

I~VESTI~ATION OF MODES OF THERMAL FRACTURE OF SOME BRITTLE MATERIALS by CHARLES R. NELSON Submitted to the De~artment of Civil Engineering on September 2, 1969, in partial fulfillment of the requirements for the degree of Doctor of Philosophy. An analysis of the temperatures and the thermal stresses in a detailed and accurate manner with the finite element technique resulted in the following ad...

Welding-induced distortion is an intrinsic phenomenon arising due to the thermally induced strain distributions in the weld and surrounding material. The distortion can be minimized during the pre-process, real-time, or postprocess stages. In the present paper, the laser forming (LF) technology is utilized for the post correction of welding-induced distortion. The out-of-plane distortion can be...

In this study, the high-cycle fatigue behavior of bridge connections subjected to distortion-induced loadings (generating multiaxial stresses) and strengthened with prestressed elements were experimentally investigated. Thereafter, appropriate critical plane-based thresholds based on modified Wohler curve method (MWCM) Fatemi-Socie's (FS) criteria used predict initiation cracks in angles consid...

High speed machining (HSM) may produces parts with substantially higher fatigue strength; increased subsurface micro-hardness and plastic deformation, mostly due to the ploughing of the round cutting tool edge associated with induced stresses, and can have far more superior surface properties than surfaces generated by grinding and polishing. Cutting edge roundness may induce stress and tempera...

Pectus carinatum (PC) is a chest deformity caused by a disproportionate growth of the costal cartilages compared to the bony thoracic skeleton, pulling the sternum towards, which leads to its protrusion. There has been a growing interest on using the 'reversed Nuss' technique as a minimally invasive procedure for PC surgical correction. A corrective bar is introduced between the skin and the th...

The goal of this work is to quantitatively assess the relationship between the reported restenosis rates and stent induced arterial stress or strain parameters through finite element method. The impact of three stent designs (Palmaz–Schatz stent, Express stent, and Multilink Vision stent) on the arterial stress distributions were characterized. The influences of initial stent deployment locatio...