clinical application of embryonic stem (es) cells faces difficulties regarding tissue rejection as well as ethical limitations. one solution for these issues is to reprogram somatic cells by the injection of their nucleus into an enucleated oocyte or zygote. however, technical complications and ethical considerations have impeded the therapeutic implications of this technology. an approach whic...

conclusions the adoption of 85 dba as the permissible exposure limit has preserved hearing threshold level among participants at 3000 hz compared to those who embraced 90 dba. patients and methods this is an intervention study done on two automobile factories. there were 203 employees exposed to noise levels beyond the action level. hearing protection devices were distributed to reduce noise le...

this paper describes the effects of induced magnetic field and partial slip on the peristaltic flow of a couple stress fluids in an asymmetric channel. the two dimensional equation of couple stress fluid are simplified by making the assumptions of long wave length and low reynolds number. the exact solutions of reduced momentum equation and magnetic force function have been computed in wave fra...

we compared the extent of temporary threshold shift (tts) and hair cell loss following high level 4 khz noise exposure with those preconditioned with moderate level 1 and 4 khz octave band noise. fifteen male albino guinea pigs (300- 350 g in weight) were randomly allocated into three groups: those exposed to 4 khz octave band noise at 102 db spl (group 1, n=5); those conditioned with 1 khz oct...

the ethanolic extract of wedelia chinensis (eewc) belonging to the family of asteraceae was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its by using on carrageenan, mediators such as histamine and serotonin induced paw oedema, and cotton pellet induced granuloma tests for its effect on acute and chronic pha...

personalized medicine as a novel field of medicine refers to the prescription of specific therapeutics procedure for an individual. this approach has established based on pharmacogenetic and pharmacogenomic information and data. the terms precision and personalized medicines are sometimes applied interchangeably. however, there has been a shift from “personalized medicine” towards “precision me...

introduction the incidence of liver damage due to steroid consumption is increasing due to the omnipresence of the idealized body image and the widespread availability of drugs via the internet. the genetic factors underlying individual susceptibility are not presently known. conclusions this case of pxr haploinsufficiency reveals transcriptional regulatory functions activated in the liver unde...

objective(s): the present study investigated the effects of microinjection of histamine and histamine h1, h2, and h3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (psc) on inflammatory pain.   material and methods: two stainless steel guide canulas were bilaterally implanted into the psc of anaesthetized rats. inflammator...

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