background: based on literature, in vitro cholesterol removal of lactic acid bacteria has been accounted for their in vivo cholesterol reduction. but recently, it has been proposed that such in vitro characteristic may not be directly relevant to their in vivo activity. the objective of this study was to find how much in vitro cholesterol reducing potential of lactobacillus plantarum a7 (la7), ...

The aim of the present work was to prepare and characterize biopolymer nanocarriers and evaluate their suitability in possible oral delivery of insulin. The egg albumin biopolymer was used to prepare nanoparticles which were further characterized by Fourier transformed Infrared spectroscopy (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), zeta potential, Dynam...

a new group of 4-(imidazolylmethyl) quinoline derivatives possessing a methylsulfonyl cox-2 pharmacophore at the para position of the c-2 phenyl ring were designed and synthesized as selective cox-2 inhibitors and in-vitro anti breast cancer agents. in-vitro cox-1 and cox-2 inhibition studies showed that all the compounds were potent and selective inhibitors of the cox-2 isozyme with ic50 value...

Tissue Sealants In article number 2100803 by Boaz Mizrahi and co-workers, an elastic biodegradable sealant is designed mixing two complementary neat (solvent-free) star shape prepolymers. This mixture, which hardens in several seconds, offers advantages over existing tissue sealants, including excellent mechanical properties degradation behavior, minimal cytotoxicity vitro biocompatibility vivo.

rate of in vitro maturation of oocytes is one of the challenges of assisted reproductive techniques. in this study we investigated the effects of supplementation of cysteamine on the rate of in vitro maturation of oocytes in two different media. germinal vesicle oocytes were collected from mouse ovary and cultured in two media (tcm199 and meme) with 0, 50, 100, 200, 500 µm/ml cysteamine. number...

background: dominant lactic acid bacteria (lab) originally isolated from traditional non-dairy fermented foods, may harbor unique characteristics such as probiotic properties. in this research, probiotic potential of dominant lab isolated from pickled garlic was studied. methods: after isolation of dominant lab from pickled garlic produced with apple cider vinegar, the isolate was identified by...

introduction: spreading depression (sd) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex. it has been shown that the dopaminergic system plays a role in migraine. sd has been suggested as a critical phenomenon in the pathophysiology of migraine. the aim of this study was to investi...

background: endometrial secretion analysis is a non-invasive and promising method in evaluation of endometrial receptivity. objective: the aim of the present study was to assess the relationship between the success rate of ivf procedures and some endometrial secretion cytokines, including interleukin-1β (il-1β), tumor necrosis factor (tnf-α), interferon gamma-induced protein 10 (ip-10), and mon...

Objective: The purpose of the current study was to investigate the in vivo (analgesic, antidiarrheal, neurological, and cytotoxic) and in vitro (antioxidant, antimicrobial, thrombolytic and anthelmintic) activity of different fractions of methanolic extract of Momordica charantia. Materials and Methods: The antioxidant property ...