introduction: certain types of human papillomavrus (hpv) are associated with cervical intraepithelial neoplasia (cin) and squamous cell carcinoma (scc). the aim of theobservations reported here was to determine whether the prognosis for invasive cancers of the uterine cervix is related to the type of human papillomavirus asociated with the tumor. material and methods: twenty patients with invas...

Gichuhi S, Macharia E, Kabiru J, et al. Topical fluorouracil after surgery for ocular surface squamous neoplasia in Kenya: a randomised, doubleblind, placebo-controlled trial. Lancet Glob Health 2016; 4: e378–85— In this Article, the definition of CIN in table 1 should have read “CIN=conjunctival intra-epithelial neoplasia”. This correction has been made to the online version as of April 7, 2017.

Extraocular sebaceous carcinoma is a relatively rare skin appendage carcinoma [1]. Although ocular sebaceous carcinoma is thought to arise from the Meibomian glands and glands of Zeis, there is no evidence that extraocular sebaceous carcinoma arises from pre-existing sebaceous glands [2]. Most sebaceous carcinomas are invasive [1], however, only a few cases of sebaceous carcinoma associated wit...

In the current study we aimed to clarify the potential of EpCAM and villin as in vivo biomarkers for both Barrett esophagus (BE)-associated neoplasia and BE versus cardiac mucosa. Immunohistochemical staining in BE with various degrees of intraepithelial neoplasia (IN), Barrett carcinoma (BC) and in normal cardiac mucosa (CM) revealed a lack of EpCam and villin in squamous esophageal epithelium...

objective(s): in developing countries and worldwide cervical cancer is an important cause of   female mortality. reports describing the frequency and pattern of abnormal pap smears in saudi arabia, using the revised bethesda system (rbs) are very few. the current study was conducted to explore the changing pattern of epithelial cell abnormalities (eca) detected in pap smears (ps) in females of ...

LS: lichen sclerosus PeIN: penile intraepithelial neoplasia L ichen sclerosus (LS) is a chronic disorder with a predilection for the anogenital area. In this anatomic area, a subset of human papillomavirusenegative neoplasms arise on the background of chronic inflammation, of which LS is the most common condition. Of these neoplastic associations, squamous intraepithelial neoplasias, including ...

Many cancers affecting the lower extremity have been described in the literature. As many podiatrists continue to fill roles as leaders in wound care, the burden and opportunity of recognition comes to the forefront. Chronic wounds can be great masqueraders of neoplasia. This case presents the diagnosis and treatment of a 48 year old male with squamous cell carcinoma of the foot as well as a re...

Purpose. Pseudoepitheliomatous hyperplasia at the limbus can mimic an ocular surface squamous neoplasia. It is an uncommon manifestation of vernal keratoconjunctivitis and has been reported previously in limbal VKC. It, however, has not been reported as a manifestation in the palpebral form of the disease and needs to be kept in the differential diagnosis of a limbal mass lesion in vernal kerat...

BACKGROUND/AIMS Topical mitomycin C (MMC) therapy has been used for treatment of ocular surface squamous neoplasia (OSSN) since 1994. Relatively few studies have reported the cellular changes in ocular surface following MMC. METHODS Impression cytology was studied in four patients with ocular surface squamous neoplasia, either primary or recurrence after previous excisional biopsy. The author...