The meningioma (ME) was originally described by Virchow in 1863 as a tumor originating from meningothelial cells that are usually found within leptomeninges and the choroid plexi of the ventricles, with a preference for the supratentorial area. Any area that is covered by the leptomeninges, however, is potentially a site of origin for meningiomas. The first report of an exclusively intracanalic...

Background: Helicobacter pylori, which is associated with many upper gastrointestinal diseases, is found in half of the population of the world. Several special stains and immunohistochemistry stain for H. pylori are available. The need for and usefulness of immunohistochemical (IHC) technique has been debated for years. Toluidine blue is a simple stain for microbiological studies and is easily...

localized leishmania lymphadenitis (l.l.l) is a self limited clinical presentation of cutaneous leishmaniasis. microscopic findings in l.l.l are very similar to toxoplasma lymphasenitis. in all cases, an intensive microscopic search should be done for leishman bodies. in this study, we describe our microscopic findings and results of our immnohistochemical (ihc) study with a panel of monoclonal...

background and objective: evaluation of tumor proliferative activity may provide a predicting parameter to estimate biologic aggression and a subsequent prognosis that has been evaluated in many malignancies. we have selected renal cell carcinoma (rcc) in this study. to determine tumor proliferative activity, ki67 antibody was applied and results were compared with apoptosis, applying p53 antib...

objective: because of the necessity of more effective treatments for the nervous system injuries and considering the role of survivin in cellular proliferation and apoptotic cell death, we have monitored survivin gene expression changes during the course of regeneration in injured sciatic nerves and also l4-l6 segments of spinal cord. materials and methods: we used adult male nmri mice as a mo...

background: colorectal adenocarcinoma is one of the most prevalent and treatable malignancies of the gastrointestinal tract. pattern of expression of the p53, p21, p16, e-cadherin and |î²|-catenin proteins are shown to be related to the prognosis of this malignancy. we aimed to compare the pattern of expression of these proteins in tumoral and nontumoral mucosal cells of cancer and on-cancer pa...

introduction: natural killer (nk) cells, of which cd56 is a specific marker, play an important role in host defense against tumors. cancer stem cells, of which aldehyde dehydrogenase isoform 1 (aldh1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. we aimed to evaluate the expression of aldh1 and cd56 in common salivary g...

background: non obstructive azoospermia (noa) is one of the causes of male infertility in which spermatogenesis process is disturbed. recent studies suggested the possible role of endothelial nitric oxide synthase (enos) in spermatogenesis process. objective: the aim of the present study is to evaluate the expression of enos in human testicular tissue in men with noa and men with normal spermat...