نتایج جستجو برای: immune processes

تعداد نتایج: 781161  

Impairments in cell migration processes may cause various diseases, among which cancer cell metastasis, tumor angiogenesis, and the disability of immune cells to infiltrate into tumors are prominent ones. Mathematical modeling has been widely used to analyze the cell migration process. Cell migration is a complicated process and requires statistical methods such as random walk for proper analys...

Journal: :The Journal of clinical investigation 2012
Christian Brede Mike Friedrich Ana-Laura Jordán-Garrote Simone S Riedel Carina A Bäuerlein Katrin G Heinze Tobias Bopp Stephan Schulz Anja Mottok Carolin Kiesel Katharina Mattenheimer Miriam Ritz Viktoria von Krosigk Andreas Rosenwald Hermann Einsele Robert S Negrin Gregory S Harms Andreas Beilhack

Understanding the spatiotemporal changes of cellular and molecular events within an organism is crucial to elucidate the complex immune processes involved in infections, autoimmune disorders, transplantation, and neoplastic transformation and metastasis. Here we introduce a novel multicolor light sheet fluorescence microscopy (LSFM) approach for deciphering immune processes in large tissue spec...

2003
W. E. Briles H. Lillehoj R. F. Wideman R. L. Taylor

s of papers 3 7 Non-MHC alloantigen genes affecting immunity. W. E. Briles*, Northern Illinois University, DeKalb, IL 60115. An alloantigen is a genetically determined cell-surface molecule detected by specific antisera. An identifying letter has been assigned to each genetic locus responsible for the eleven distinct families of alloantigens A, C, D, E, H, I, J, K, L, P, and R. The genes of eac...

Journal: :iranian journal of neurology 0
mohaddeseh behjati department of cardiology, school of medicine, cardiovascular research center and heart failure research center, isfahan cardiovascular research institute, isfahan university of medical sciences, isfahan, iran. masoud etemadifar department of neurology, school of medicine, isfahan university of medical sciences, isfahan, iran. morteza abdar esfahani department of cardiology, school of medicine, isfahan university of medical sciences, isfahan, iran.

multiple sclerosis (ms) is a chronic auto-immune disease. most therapeutic strategies for treatment of this disease direct immune modulation and control of inflammatory processes. first-line therapeutic agents showed moderate efficacy and frequent side-effects with moderate efficacy in trials. their parental administration and limited long-term adherence restrict their efficacy compared with se...

Journal: :Frontiers in bioscience : a journal and virtual library 2007
Bethany M Tesar Daniel R Goldstein

The innate immune system is an ancient, conserved pathogen response system that lays the foundation for self/non-self discrimination. The cells of the innate immune system are responsible for recognizing the highly conserved molecular motifs of microbial pathogens and represent the first line of immunological defense as well as contributing to the activation of the adaptive immune response. Tol...

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