نتایج جستجو برای: immune modulator
تعداد نتایج: 283896 فیلتر نتایج به سال:
BACKGROUND Isolated fucoidans from brown marine algae have been shown to have a range of immune-modulating effects. This exploratory study aimed to determine whether a seaweed nutrient complex containing a blend of extracts from three different species of brown algae plus nutrients is safe to administer and has biological potential as an immune modulator. The study was undertaken as an open-lab...
Lifelong infection is a hallmark of all herpesviruses, and their survival depends on countering host immune defenses. The human gammaherpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) encodes an array of proteins that contribute to immune evasion, including modulator of immune recognition 2 (MIR2), an E3 ubiquitin ligase. Exogenously expressed MIR2 downregulates the surface expression o...
Background and Objectives: Kerman Province, especially city of Bam in the southeast part of Iran, is epidemics for dry type cutaneous leishmaniasis (DTCL). This study was conducted to compare the effect of different treatments on parasite DNA load following therapies using Real-Time PCR method. Materials and Methods: Fifteen patients were divided into three groups under therapy with intralesio...
Transendothelial trafficking of immune cells into the central nervous system (CNS) and disruption of the blood brain barrier (BBB) are pathophysiological hallmarks of neuroinflammatory disorders like multiple sclerosis (MS). Accumulating evidence suggest that oxidative stress plays a major role in the pathogenesis of MS, whereas a specific influence of oxidative stress on BBB dysfunction in MS ...
Abstract IFN-induced protein with tetratricopeptide repeats (IFITs), known as canonical IFN-stimulated genes (ISGs), play critical roles in regulating immune responses against pathogens and maintaining homeostasis. How the IFIT5 regulates innate is rarely reported remains enigmatic. In this study, we discover that human (hIFIT5) functions a negative regulator of type I IFN (IFN) pathway HEK293T...
The innate defense system of the female mucosal genital tract involves a close and complex interaction among the healthy vaginal microbiota, different cells, and various proteins that protect the host from pathogens. Vaginal lactobacilli and lactoferrin represent two essential actors in the vaginal environment. Lactobacilli represent the dominant bacterial species able to prevent facultative an...
In this research, design and fabrication of an integrated heterodyne electrooptic modulator in lithium niobate have been presented. In this modulator, the waveguide is made by using proton exchange process; to exert two high frequency signals, deposited electrodes with Mach-Zender arms between them are used. In this method, every electrical signal is applied on one of the Mach-Zender arms, so t...
Background and purpose : Toxoplasma gondii is an obligate interacelullar parasite that infect a wide variety of nucleated cells in its intermediate hosts. Tachyzoites of Toxoplasma gondii in able to multiply in mouse macrophages. Inducing synthesis of nitric oxide (NO) by macrophages is an important mechanism of the host defense against interacelullar infection in mice. The 1.25 dihydroxy vit...
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