Preceding papers have shown (1, 2, 3, 4, 5) that in the rheumatic subject one factor essential for the development of acute rheumatism is the magnitude of the immune response to hemolytic streptococcus infection. The mechanism involved in the rheumatic process is unknown. The present paper deals with an attempt to diminish the. patient's antibody production for the purpose of modifying the rheu...

By DONALD M. ERvIN, M.D., RICHARD M. CHRISTIAN, M.D., AND LAWRENCE E. YOUNG, M.D. H EMOLYTIC reactions resulting from transfusion of group 0 plasma into group A recipients, while not common, have been reported with increasing frequency during the past few years.’5 Reactions of this type are usually not as dramatic or as severe as those resulting from transfusion of incompatible whole blood and ...

Auto Immune Hemolytic Anemia (AIHA) is a rare entity in children. We report a case of an adolescent girl with AIHA, which was precipitated by chicken pox. Clinical course over 3 years, till remission is described.

BACKGROUND Non-ABO alloantibodies are frequently implicated in hemolytic transfusion reactions and are a leading cause of transfusion-related mortality. Detection of clinically significant non-ABO alloantibodies is reliant on an antibody screen, which is prone to clerical, technical, and reagent error. Data on the frequency of false-negative antibody screens due to the occurrence of these error...

The clinical need to rapidly and correctly differentiate beta-hemolytic streptococci into Lancefield groups has prompted the development of commercially available rapid agglutination techniques. A modified Streptex (Wellcome Diagnostics, Research Triangle Park, N.C.) technique and the PathoDx latex Strep Grouping Kit (Diagnostic Products Corporation, Los Angeles, Calif.) technique were applied ...

BACKGROUND Blood transfusion is imperative when treating certain patients; however, it is not risk free. In addition to the possible transmission of contagious infectious diseases, incidents can occur immediately after transfusion and at a later time. AIMS This study aimed to examine the immediate transfusion incidents reported in a regional blood bank in the state of Minas Gerais between Dec...

the most common form of acquired hemolytic anemia is associated with what appears to be autologous igg hemagglutinins. these anti-bodies may arise unexpectedly and in the absence of any recognizable underlying disease. however, they are observed not uncommonly as a complication of systemic lupus erythematosis, chronic lymphatic leukemia, lymphosarcoma, ulcerative colitis, etc. 'the red cells of...