dans cet article, l'auteur tudie la creation d'une voie ferre interurbaine, de la banlieue ou urbaine, et essaie de d6terminer le nombre optimal de stations pour une longueur donnee de la ligne; compte tenue d'une repartion du trafic, ie long de la ligne en question qui est suppose etre connue. le critere d'optimalisation est le temps total perdu par l'ensemble des usag...

dans cet article i' intervalle entre deux trains successifs a ete etudie en fonction de leur vitesses dans deux cas differents. dans ie premier cas ,on suppose que la vitesse des deux trains a une valeur constante, et on etudie les variations de l'intervalle minimum en fonction de la vitesse on determine la vitesse optimale et on etudie les variations de l'intervalle minimum en f...

BACKGROUND In March 2008, the National Institute for Health and Care Excellence recommended stopping antibiotic prophylaxis (AP) for those at risk of infective endocarditis (IE) undergoing dental procedures in the United Kingdom, citing a lack of evidence of efficacy and cost-effectiveness. We have performed a new economic evaluation of AP on the basis of contemporary estimates of efficacy, adv...

background: molecules expressed on the surface of infected erythrocytes (ie) with plasmodium falci-parum play important roles in malaria pathogenesis and immune evasion. some of these molecules are specific adhesive ligands mediating adhesion of ie to the vascular endothelium. in the current study, the antigens exposed on the surface of ie with different isolates and various binding subpopulati...

Human herpesvirus 6 (HHV-6) like other herpesviruses, expresses sequentially immediate early (IE), early, and late genes during lytic infection. Evidence of ability to establish latent infection has not been available, but by analogy with other herpesviruses it could be expected that IE genes that regulate and transactivate late genes would not be expressed. We report that peripheral blood mono...

Patent ductus arteriosus (PDA) accounts for approximately 10% of all congenital heart diseases, with an incidence of at least 2-4 per 1000 term births. Closure of the large, hemodynamically significant PDA is established as the standard of care, and can be performed safely and effectively using either surgical or transcatheter methods. The appropriate management of the very small, hemodynamical...

BACKGROUND Few studies have compared the accuracy of [(18)F]fluorodeoxyglucose (FDG) PET to the accuracy of clinical and pathologic diagnosis in dementia patients. METHODS Forty-four individuals with dementia, cognitive impairment, or normal cognitive function underwent clinical initial evaluation (IE) and PET scanning and were followed up for approximately 4 years until a final evaluation (F...

Objective: Reconstructive surgery of the lower urinary tract in children is reported with a high complication rate. The aim was to evaluate the complication rate at our institution. Material and methods: Between 2000 and 2010, 41 boys and 19 girls were consecutively operated on with augmentation with ileum (45), alternative CIC-channel (57) and bladder neck plasty (42) in isolation or as combin...

CONTEXT Progressively more osteopathic graduates are seeking training opportunities in programs accredited by the Accreditation Council on Graduate Medical Education (ACGME). OBJECTIVE To determine if family medicine residency training program choice (ie, allopathic [ACGME], osteopathic, or dually accredited) has an impact on professional satisfaction levels among recent osteopathic medical s...

BACKGROUND Interleukin 22 (IL-22) is emerging as a key cytokine for gut epithelial homeostasis and mucosal repair. Gut disruption is a hallmark of human immunodeficiency virus (HIV) infection. Here, we investigated IL-22 production and gut mucosal integrity in HIV type 1 (HIV-1)-infected individuals receiving long-term antiretroviral therapy (ART). METHODS Biopsy specimens from 37 individuals...