OBJECTIVE To determine whether, in dogs with naïve multicentric lymphoma, neutrophilia at the time of initial diagnosis was associated progression-free survival (PFST) or overall response rate (ie, percentage a complete partial remission) and whether neutrophil-to-lymphocyte ratio PFST. ANIMALS 30 lymphoma (including 16 treated cyclophosphamide, doxorubicin, vincristine, prednisone [CHOP]–based...

T he risk of infective endocarditis (IE) remains a major concern in patients with congenital heart disease (CHD), whether unrepaired, palliated, or corrected. The overall incidence of endocarditis in adults with CHD has been reported to be 11 per 100 000 person-years, which is a considerable increase compared with the general population, in which a rate of 1.5 to 6.0 per 100 000 patient-years h...

BACKGROUND Bisphosphonates have profound effects on bone physiology, and could modify the process of metastasis. We undertook collaborative meta-analyses to clarify the risks and benefits of adjuvant bisphosphonate treatment in breast cancer. METHODS We sought individual patient data from all unconfounded trials in early breast cancer that randomised between bisphosphonate and control. Primar...

We used an analysis of deuterium values (oD) of 151 Wood Thrush (Hylocichla mustelina (J.F. Gmelin, 1789)) feathers collected during the breeding season at the Piedmont National Wildlife Refuge in Georgia, USA, to determine fidelity to the study site. We compared oD values in feathers of birds with known molt locations and birds with unknown molt locations. Mean feather value of oD was -24.8%0 ...

Glutamine (GLN) has many types of biological activity in rats, including anti-inflammatory, antioxidative stress, and anti-apoptosis effects. However, little is known about the effects GLN on bovine mammary epithelial cells (BMEC). γ-d-Glutamyl-meso-diaminopimelic acid (iE-DAP) a cell wall peptidoglycan component gram-negative bacteria that can be recognized by intracellular receptor nucleotide...

We reconstructed the regulated induction of delayed-early (DE) transcription that occurs during herpes simplex virus (HSV) infection by using a transient expression system in which recombinant target genes were cotransfected into Vero cells together with intact activating genes. Plasmids containing cloned HSV-1 or HSV-2 immediate-early (IE) genes stimulated by up to 100-fold the expression from...

Aims There are scant comparative data quantifying the risk of infective endocarditis (IE) and associated mortality in individuals with predisposing cardiac conditions. Methods and results English hospital admissions for conditions associated with increased IE risk were followed for 5 years to quantify subsequent IE admissions. The 5-year risk of IE or dying during an IE admission was calculat...

Abstract. Objective: In this pilot study, the authors examined the effectiveness of a 4-week resilience intervention to enhance resilience, coping strategies, and protective factors, as well as decrease symptomatology during a period of increased academic stress. Participants and Methods: College students were randomly assigned to experimental (n = 30) and wait-list control (n = 27) groups. The...