conclusions administration of aeds in general and levetiracetam in particular should be based on attention to pharmacokinetic behavior in terms of monotherapy or polypharmacy. case presentation two cases were studied, one patient was a 32-year-old male and the other was a 14-year-old female. the key words relevant to search topics were surveyed using pubmed (united states national library of me...

The molecular basis of idiopathic generalized epilepsy remains poorly understood. Absence epilepsy with 3 Hz spike-wave EEG is one of the most common human epilepsies, and is associated with significant morbidity. Several spontaneously occurring genetic mouse models of absence epilepsy are caused by dysfunction of the P/Q-type voltage-gated calcium channel CaV2.1. Such mice exhibit a primary ge...

Abstract Background Epilepsy is a prevalent disease worldwide. Executive functions and social cognition are essential in daily living functioning, academic performance, adjustment. This study attempts to investigate the executive ability abstract concepts adolescents who have idiopathic generalized epilepsy assess if deterioration can predict concepts. Sixty with aged between 12 19 collected fr...

Juvenile myoclonic epilepsy (JME) is a common idiopathic generalized epilepsy syndrome with the prevalence of 6 to 12% among all patients with epilepsy based on hospital and clinical records [1, 2]. As a specific electroclinical syndrome, it is characterized by a genetic predisposition, no evidence of neurological or intellectual deficit and by mandatory or typical myoclonic seizures alone (irr...

PURPOSE To identify the prevalence, clinical characteristics and routine EEG features of the syndrome of eyelid myoclonia with absences (EMA) using a retrospective case control study design. METHODS EEGs from 1996 to 2005 were searched using the following keywords: eyelid flutter, eyelid blinking, tics, idiopathic generalized epilepsy, clinical absence, atypical absence and photoparoxysmal re...

The early prediction of intractability is a major challenge in epileptology. Some prognostic factors have been pointed out, most of which simply underlined that partial epilepsy is more difficult to control than idiopathic generalized epilepsy (IGE). Indeed, the main predictors are the presence of a brain lesion demonstrated by neuroimaging or suggested by a neurological deficit or a developmen...

The early prediction of intractability is a major challenge in epileptology. Some prognostic factors have been pointed out, most of which simply underlined that partial epilepsy is more difficult to control than idiopathic generalized epilepsy (IGE). Indeed, the main predictors are the presence of a brain lesion demonstrated by neuroimaging or suggested by a neurological deficit or a developmen...