PURPOSE To evaluate a noninvasive technique to detect the leakage point of central serous chorioretinopathy (CSR), using a polarimetry method. DESIGN Prospective cohort study. METHODS SETTING Institutional practice. PATIENTS We examined 30 eyes of 30 patients with CSR. MAIN OUTCOME MEASURES Polarimetry images were recorded using the GDx-N (Laser Diagnostic Technologies). We computed ...

Fig. 1 – Progressive reduction of macular serous detachment after treatment with subthreshold laser on the active extra foveal leak point. Fluorescein angiography in left eye in early stage (A) and in late stage (B) illustrating fluorescein extravasation in superior/nasal focal point, the origin of the subretinal fluid which causes neuroepithelium serous detachment with macular involvement (D) ...

PURPOSE A clear link between several variants in genes involved in the complement system and chronic central serous chorioretinopathy (CSC) has been described. In age-related macular degeneration, a disease that shows clinical features that overlap with CSC, both genetic risk factors and systemic activation of the complement system have previously been found. In this case-control study, we asse...

C horoidal hemangioma is a relatively rare, benign vascular hamartoma. The circumscribed type is classically unilateral and is believed to be congenital in origin.1,2 Circumscribed choroidal hemangioma typically appears as a slightly oval or round, red-orange mass in the macular or perimacular region of the choroid, often with clinically indistinct borders.1-3 Although choroidal hemangioma is b...

BACKGROUND Central serous chorioretinopathy (CSC) has been traditionally treated with laser photocoagulation. We thought that transpupillary thermotherapy (TTT) utilizing a lower temperature than that of conventional laser photocoagulation might minimize permanent retinal and choroidal damage. Studies suggest that undesirable effects on vision due to TTT are minimal even if it is applied to fov...

CLINICAL CASE A 37-year-old man was referred because of a bilateral loss of visual acuity and metamorphopsia. On examination there was yellowish exudation bilaterally associated with serous retinal detachments, corresponding to hyperfluorescence spots in the early stage of fluorescein angiography. Photocoagulation of the leakage spots was performed in both eyes. Six months later he had recovere...

Central serous chorioretinopathy (CSC) is a relatively common posterior segment disease characterized by serous detachment of the neurosensory retina. Altered function of the retinal pigment epithelium (RPE) and choroidal vascular hyperpermeability suggestive of choroidal vascular compromise have been thought to play important roles in the pathogenesis of CSC [1,2]. CSC typically affects middle...

Central serous chorioretinopathy (CSC) is a retinal disorder that primarily affects young (20to 50-year-old) white men, although it is seen occasionally in older patients and females. CSC is characterized by avascular focal leakage through the retinal pigment epithelium (RPE), resulting in serous detachment of the neurosensory retina. The course is usually self-limiting and in most cases resolv...

Central serous chorioretinopathy (CSC) affects roughly 10 men and two women per 100,000 people, and they are often younger, working-aged individuals with high visual demands. Randomized clinical trials in CSC are scarce and typically evaluate dozens of patients1-12 (Table, page 11) rather than the hundreds or even thousands of patients evaluated in trials for age-related macular degeneration (A...

Funding/Support: This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York, and the Jack A. and Elaine D. Klieger Professorship, Medical College of Wisconsin, Milwaukee. Online-Only Material: The video is available at http: //www.archophthalmol.com. Additional Contributions: Deb Wahlers and Adam Dubis provided technical assistance in pr...