نتایج جستجو برای: ibandronate

تعداد نتایج: 387  

2005
Silvano Adami Maurizio Rossini

The primary objective of Paget’s disease treatment is the relief of symptoms, but treatment is also commonly prescribed to prevent the development of late complications in asymptomatic subjects with active disease (i.e., above normal serum alkaline phosphatase [bALP]). An aggressive course of treatment is recommended before surgery at the site of a pagetic lesion, the aim being to reduce as muc...

Journal: :JAMA internal medicine 2017
Casey Carroll Ahmed Hassanin

Story From the Front Lines An83-year-oldwomanwith a history of atrial fibrillation and congestive heart failure was admitted to the hospital after presenting with lightheadedness and palpitations secondary to atrial fibrillation with rapid ventricular response. This was her third admission for atrial fibrillationwithuncontrolledheartrate inthepast6months.Pharmacy records indicated she had not r...

Journal: :Haematologica 2006
Meletios A Dimopoulos Efstathios Kastritis Athanasios Anagnostopoulos Ioannis Melakopoulos Dimitra Gika Lia A Moulopoulos Christina Bamia Evangelos Terpos Konstantinos Tsionos Aristotelis Bamias

Osteonecrosis of the jaw (ONJ) has been associated with the use of pamidronate and zoledronic acid. ONJ was assessed prospectively since July 2003 in 202 patients with multiple myeloma (MM) who received bisphosphonates since April 1995. Fifteen patients (7.4%) developed ONJ. The median time of exposure to bisphosphonates was 39 months for patients with ONJ compared to 28 months (p=0.048) for pa...

2013
Carine Tabarani Raffaele Volpi Fawzi Riachi

We can distinguish three generations of bisphosphonate. The first is formed of the non-aminobisphosphonate (Etidronate, Clodronate), the second correspond to the aminobisphosphonates (Pamidronate, Alendronate) that are 100 to 500 times more powerful, and the third generation (Ibandronate, Risedronate and Zoledronate) that is 10 to 20 times more powerful than the previous generations in terms of...

Journal: :Clinical advances in hematology & oncology : H&O 2012
Anuj Mahindra Samantha Pozzi Noopur Raje

More than 80% of patients with multiple myeloma (MM) have osteolytic bone disease, which increases the risk of skeletal-related events (SREs) such as pathologic fracture, spinal cord compression, and the need for radiotherapy or surgery. Bone disease is primarily due to increased osteoclastic activity and impaired osteoblast activity. Bisphosphonates are pyrophosphate analogues with high bone a...

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