Humans with long-standing sleep apnea show mixed responses to serotonergic therapies for obstructive sleep apnea. We hypothesize that long-term intermittent hypoxia may result in oxidative injury to upper airway motoneurons, thereby diminishing serotonergic motoneuronal excitation. Unilateral serotonin and glutamate agonist and antagonist microinjections into the hypoglossal motor nuclei in adu...

Study Objective. To describe the clinical presentation, evaluation, and treatment of a hypoglossal schwannoma. Methods. We report an unusual case of a hypoglossal schwannoma presenting as a pulsatile level II neck mass at the bifurcation of the external and internal carotid arteries, mimicking a carotid body tumor. Radiologic findings are reviewed in detail. Results. A 59-year-old female presen...

An unusual case of peripheral hypoglossal nerve palsy, caused by lateral position of the external carotid artery and an abnormally high carotid bifurcation is reported. Improvement followed ligation and cutting of the external carotid artery at its origin.

Interfacing with the peripheral nervous system is a powerful method for diagnosing and treating several diseases, such as drug-resistant epilepsy depression. In most clinical applications, large nerves vagus hypoglossal nerve are targeted. Large carry multiple fibers, maintaining selectivity of specific target response demands complex stimulation strategies. As trunks bifurcate toward their dis...

To cite: Kim JY, Han SW. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-202781 DESCRIPTION Occurrence of hypoglossal nerve palsy (HNP) accompanied with other cranial nerve palsies is not an uncommon finding. However, isolated HNP is a rare finding and represents a diagnostic challenge. Awoman in her late 70 s was referred to the neurology department due to ...

The migration pattern and fate of cells of the occipital somites and overlying ectoderm have been described for the chick embryo with particular reference to the development of the hypoglossal musculature. Tritium-labelled thymidine (0-5-10 /tCi per egg) was used as a cell-specific marker. Occipital somites (2-5) with overlying ectoderm were transplanted orthotopically from labelled donor embry...