A 47 year old woman with pure autonomic failure complained of dizziness during emotional stress. Emotional stimuli have not previously been reported to cause hypotension in patients with autonomic failure. In the patient, ambulatory blood pressure recording revealed severe hypotension (50/30 mm Hg) after a stressful event. During a tilt table test, hyperventilation was shown to cause a signific...

The prophylactic inhalation of disodium cromoglycate lessens the exacerbations which occur in some asthmatic patients after voluntary hyperventilation. Reasons are given for considering this to be a possible mechanism for certain types of emotional exacerbation of the disease and for disodium cromoglycate giving sypmtomatic relief of asthma disproportionate to the improvement in routine measure...

Raab (1), in a study dealing with the effect of hyperventilation on the blood pressure of patients with arteriolar hypertension, concluded that there is a direct and constant relationship between the level of the blood pressure in patients with essential hypertension and the extent to which the CO2 tension of the arterial blood (alveolar CO2 tension) is lowered. The assumption was that hyperven...

A double blind, placebo controlled compa-rison was made of the effects of nebulised ipratropium bromide (0O05 and 0-5 mg) and salbutamol (0-25 and 2-5 mg) on lung function and the airway response to hyperventilation in eight normal subjects. Both agents at both doses caused similar baseline bronchodilatation, confirming the presence of resting bronchomotor tone. The overall mean increases as pe...

Isocapnic hyperventilation dose response curves were constructed for 11 asthmatic children before and after pretreatment with placebo or ipratropium bromide, 40-1500 micrograms given by inhalation, on three separate days. The response before and after placebo was highly reproducible (within subject coefficient of variation 7.5%, 18%, and 22% for intervals of two hours, within two weeks, and ove...

1. Yasue H, Nagao M, Omote S, Takizawa A, Miwa K, Tanaka S: Coronary arterial spasm and Prinzmetal’s variant form of angina induced by hyperventilation and Tris-buffer infusion. Circulation 5856, 1978. 2. Girotti LA, Crosatto JR, Messuti H, Kaski JC, Dyszel E, Rivas CA, Araujo LI, Vetulli HD, Rosenbaum MB: The hyperventilation test as a method for developing successful therapy in Prinzmetal’s a...

Carbon dioxide is stored in the body in various forms, including carbonic acid, bicarbonate and carbamino compounds. The various stores of CO2 can be considered to be in the lung, blood, soft tissues and bone. In an adult human, these stores are thought to be in the order of 120 liters of CO2.’ It is common knowledge that hyperventilation will reduce the level of CO2 in the blood; however, only...

BACKGROUND AND PURPOSE We conducted this study to define the relationship between the hyperventilation-induced EEG changes (HV-EEG changes) and PCO2. METHODS In consecutive EEG recordings of 190 patients, we gathered data on PCO2 during the hyperventilation procedure. The data included baseline PCO2 (B-PCO2), PCO2 after 5 min of hyperventilation (5 min-PCO2), the mean value of the PCO2 (M-PCO...

Background: Although several treatment strategies to enhance the efficacy of electroconvulsive therapy (ECT) have been discussed, there have been no reports on the combined use of these treatments. The purpose of this study was to evaluate the efficacy and safety of concurrent use of moderate hyperventilation and a reduced dose of propofol combined with divided remifentanil in ECT practice. Met...