Objective: To evaluate the relationship between central obesity (Abdominal adiposity), measured by Waist/Hip ratio and the development of Coronary Heart Disease in adult population of district Swat. Methodology: The study comprised of 100 subjects, 34 Control, 33 Hypertensive subjects and 33 subjects with Coronary Heart Disease. Weight, Height, Waist/Hip ratio and Blood Pressure of subjects wit...

Introduction: The adoption of a sedentary lifestyle is major contributor to the development disease as well morbidity and mortality rates. People who have high blood pressure can benefit from regular physical activity since it lowers their pressure. A lower body fat percentage connected with risk developing when engaging in activity. There clear correlation between mass index (BMI) (BF%) terms ...

BACKGROUND There are substantial differences in the distribution of adipose tissue between women and men. We assessed the sex-specific relationships and their differences between measures of general and central adiposity and the risk of incident myocardial infarction (MI). METHODS AND RESULTS Between 2006 and 2010, the UK Biobank recruited over 500 000 participants aged 40 to 69 years across ...

The level of the obese gene product leptin is often positively correlated with body weight, supporting the notion that hyperleptinemia contributes to obesity-associated cardiac dysfunction. However, a link between leptin levels and cardiac function has not been elucidated. This study was designed to examine the role of leptin deficiency (resulting from a point mutation of the leptin gene) in ca...

Our objective was to determine whether bezafibrate, a hypotriglyceridemic drug and peroxisome proliferator-activated receptor (PPAR)-alpha agonist, is ketogenic and increases fatty acid oxidation in humans. We measured fatty acid metabolism and ketone levels in 13 mildly hypertriglycemic adults (67 +/- 11 years old) during 2 metabolic study days lasting 6 h, 1 day before and 1 day after bezafib...

OBJECTIVES A "proof-of-concept" study to examine the feasibility of wearing an Actigraph GT3X+ at the Chest (resembling a neck pendant) for physical activity measurement. DESIGN A convenience sample of 45 healthy adults (23 male, mean age 20.0±4.5 years) was included in data analysis. METHODS Participants simultaneously wore three GT3X+ accelerometers, on the Waist, Wrist, and Chest and com...