It has been suggested that low nephron number contributes to glomerular hypertension and hyperperfusion injury in progressive chronic kidney disease (CKD). The incidence of CKD in Japan is among the highest in the world, but the reasons remain unclear. We estimated total nephron (glomerular) number (NglomTOTAL) as well as numbers of nonsclerosed (NglomNSG) and globally sclerosed glomeruli (Nglo...

INTRODUCTION Despite a high worldwide prevalence of left ventricular hypertrophy among black patients, the association of a specific left ventricular geometric pattern with left ventricular dysfunction is rare. The aim of this study was to explore the possibility of such an association in Nigerian hypertensives. METHODS This was a retrospective study consisting of 188 treated hypertensives. E...

BACKGROUND It is not known whether abnormalities of left ventricular diastolic function are influenced by the various cardiac geometric patterns in Nigerians with newly diagnosed systemic hypertension. OBJECTIVE To evaluate the relationship between the parameters of left ventricular diastolic function and the geometric patterns in this group of patients. METHODS Two-dimensional, guided M-mo...

BACKGROUND One important objective defined in the Healthy People 2010 report was to improve blood pressure (BP) control to < 140/90 mm Hg in 50% of all hypertensive patients. Because the US population is becoming older, more obese, and ethnically diverse, the health and economic benefits of reaching this goal become more valuable each year. Hypertension control rates are currently at approximat...

Young adult (X- = 29) and middle aged (X- =50) hypertensive and normotensive subjects were compared with respect to seven neuropsychological test scores derived from tests on the Halstead-Reitan battery. Age main effects, with inferior performance for the middle aged subjects, were observed for the localization and time portions of the Tactile Performance Test (TPT) and for the Trail Making A t...

The decline in blood pressure (BP) in essential hypertensives following hospitalization may result from: 1) regression toward the mean; 2) reduction of anxiety as patients habituate to a new environment; 3) the placebo effect of medication; and 4) an independent effect of hospitalization itself. A randomized crossover study of 12 essential hypertensives demonstrated a fall in supine blood press...

OBJECTIVES To investigate the association of smoking habits with blood pressure (BP) and intraocular pressure (IOP), and to examine whether the smoking-BP association is related to the IOP level. METHODS This study was conducted on the basis of a cross-sectional design using annual health check-up data during one-year between August, 1999 and August, 2000 for 611 middle and old-aged Japanese ...

We read with interest the recent paper of Barbagallo et al. entitled “Oral magnesium supplementation improves vascular function in elderly diabetic patients” [1]. The authors conclude that an oral magnesium therapy positively influences brachial artery endothelial function in elderly diabetic hypertensives. In this context it is well known that endothelial function has been consistently found a...

This review briefly considers the hypothesis that a generous dietary sodium intake contributes to the development or maintenance of essential hypertension. Three lines of evidence are presented that are not mutually exclusive. Epidemiological studies examining sodium intake, prevalence of hypertension, and increases of blood pressure with age provide circumstantial support for the concept that ...

Objective: The objective of the study was to compare blood mmHg, respectively. In group B, they were unchanged during pressure (BP) biofeedback treatment (BF) effects between the same period but later suppressed by BF. Under BF, pulse white-coat hypertension and essential hypertension. Methods: and respiratory rates were significantly higher, and elevation Fifteen white-coat hypertensive out-pa...