OBJECTIVE To detect the hydroxyapatite component of vascular calcification in vivo so that the process of calcium deposition can be studied in transgenic model systems. METHODS AND RESULTS We have previously developed a near-infrared fluorescent bisphosphonate derivative that binds with high affinity and specificity to hydroxyapatite, and an intraoperative near-infrared fluorescence imaging s...

PURPOSE To investigate the biocompatibility of hydroxyapatite composite (hydroxyapatite, plaster of Paris, and chitosan) impregnated with gentamicin, fosfomycin, imipenem, or amphotericin B. METHODS The interactions of the extract from each drug against osteoblast were tested using the methylthiotetrazole test. RESULTS Extracts from all drugs showed good biocompatibility at concentrations v...

BACKGROUND The aim of the present study was to prepare hydroxyapatite (HA) and then characterize its effect on bone integration in a rabbit tibial defect model. The bone formation with different designs of HA was compared and the bony integration of several graft materials was investigated qualitatively by radiologic and histologic study. METHODS Ten rabbits were included in this study; two h...

in the present work, the effect of ca(no3)2.4h2o and (nh4)2hpo4 primary solutions as the beginning materials in synthesis of a calcium phosphate phase, was examined. so, we investigated the wet chemical reactions in solution at different temperatures by a hydrothermal condition aimed at hydroxyapatite (ca10(po4)6(oh)2); (hap) synthesis. the powders were investigated by xrd,sem, fe-tem, hrtem, e...

hydroxyapatite (ha) nano-rods with uniform morphology and controllable size have been successfully synthesized in the presence of cationic and non-ionic surfactants by a hydrothermal method. (nh4) 2hpo4 and ca(no 3)2.4h2o were used as the phosphorus and calcium sources, respectively. the composition of synthesized powders was characterized using x-ray diffraction, and fourier transform infrared...

In a previous paper we formulated the fixed-charge multiple knapsack problem (FCMKP), and developed an exact algorithm to solve this problem to optimality by combining pegging test and branch-and-bound technique. Although the developed algorithm was quite successful for instances with small number of knapsacks (m), for larger m the problem was hard to solve by this method. Here we present some ...

Manufacturing rough plans and detailed schedules must establish a compromise between antagonistic optimization criteria: meet as much as possible of the established and expected customer demand; deliver customer demands on time; reduce production costs (processing costs, resource usage costs, setup costs, cleaning costs); keep little value in inventories without risking starvation, and so on. U...

In this study, a full-length cDNA of the acyl-ACP thioesterase, AhFatA, was cloned from developing seeds of Arachis hypogaea L. by 3'-RACE. Sequence analysis showed that the open reading frame encodes a peptide of 372 amino acids and has 50-70% identity with FatA from other plants. Real-time quantitative PCR analysis revealed that AhFatA was expressed in all tissues of A. hypogaea L., but most ...

Biomineralization is an important process, which is often assisted by biomolecules. In this paper, the effect of chondroitin sulfate on the crystallization of hydroxyapatite was examined quantitatively based on a generic heterogeneous nucleation model. It is found that chondroitin sulfate can suppress the supersaturation-driven interfacial structure mismatch between the hydroxyapatite crystal a...

Introduction: The aim of this study was to evaluate the sealing ability of Bioactive glass (BG) and Bioactive glass-Hydroxyapatite (BG-HA) in comparison to Mineral Trioxide Aggregate (MTA). Methods: The sealing ability of Bioactive glass and Bioactive glass-hydroxyapatite mixed with glass ionomer cement and Mineral Trioxide Aggregate used as retrograde filling material was assessed by bacterial...