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HE PHARMACEUTICAL INDUSTRY has as its objective the discovery of important new medicines and vaccines to prevent and alleviate diseases and to improve health and the quality of life. Merck has been doing that successfully since 1933, when George W. Merck opened the first laboratory in Rahway, New Jersey. Through the efforts of its research scientists, the company has contributed drugs and vacci...

Disclosure: Prof Simon Travis has been an advisor to, in receipt of educational or research grants from, or an invited lecturer for AbbVie, Amgen, Asahi, Biogen, Boehringer Ingelheim, BMS, Cosmo, Elan, Ferring, FPRT Bio, Genentech/Roche, Genzyme, Glenmark, GW Pharmaceuticals, Lilly, Merck, Novartis, Novo Nordisk, Ocera, Pfizer, Receptos, Shire, Santarus, SigmoidPharma, Synthon, Takeda, Tillotts...

This paper reports the results of a study designed in close collaboration with Merck-Medco to identify key barriers to the success of their customer relationship management. To identify the key factors, we first used focus groups of principle users of the system to brainstorm and generate a list of scenarios and issues. A team of managers, supervisors and customer service representatives then c...

Severe gastrointestinal-tract injury due to ingestion of caustic substances is not an infrequent problem in the emergency department. We report the case of a 57-year-old male who developed massive hemorrhagic, caustic gastric necrosis due to the ingestion of a non-diluted solution containing hydrochloric acid, which propitiated an urgent surgical procedure. The esophago-gastrectomy specimen sho...

Hydrochloric acid (HCl) is an important mineral acid with many uses, including the pickling of steel, acid treatment of oil wells and chemical cleaning and processing. This acid is extremely corrosive and its aggressiveness can change drastically depending on its concentration, the temperature and contamination by oxidizing impurities. One of the most commonly encountered oxidizing impurities i...