نتایج جستجو برای: hydralazine

تعداد نتایج: 1395  

Journal: :Hypertension 2001
S Sanada M Kitakaze K Node S Takashima A Ogai H Asanuma Y Sakata M Asakura H Ogita Y Liao T Fukushima J Yamada T Minamino T Kuzuya M Hori

Chronic inhibition of NO synthesis induces cardiac hypertrophy independent of systemic blood pressure (SBP) by increasing protein synthesis in vivo. We examined whether ACE inhibitors (ACEIs) enalapril and temocapril and angiotensin II type-I receptor antagonists (angiotensin receptor blockers [ARBs]) losartan and CS-866 can block cardiac hypertrophy and whether changes in activation of 70-kDa ...

Journal: :Japanese Journal of Hospital Pharmacy 1980

2010

Background/Aims: The purpose of this study was to examine the effects of hypertension and nitric oxide (NO) inhibition on myogenic tone in uterine arteries during pregnancy. Methods: Premyometrial radial uterine arteries from nonpregnant and late pregnant Sprague-Dawley rats were evaluated for myogenic reactivity from the following groups: control, hypertensive/NO-inhibited ( L -NAME treatment)...

Journal: :Japanese Journal of Hospital Pharmacy 1980

2005
MICHAEL ARTMAN MARK D. PARRISH

We evaluated the acute hemodynamic responses to hydralazine during cardiac catheterization in eight infants (ages 1.0 to 5.5 months) with congestive heart failure due to complete atrioventricular canal defect. Hydralazine administered intravenously (0.5 to 1.0 mg/kg body weight) increased heart rate and systemic blood flow and decreased mean right atrial pressure, systemic and pulmonic arterial...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2013
Tami L Swenson John E Casida

Aldehyde oxidase (AOX) metabolizes many xenobiotics in vitro, but its importance in vivo is usually unknown relative to cytochrome P450s (CYPs) and other detoxification systems. Currently, the most important insecticides are neonicotinoids, which are metabolized in vitro by AOX on reduction of the nitroimino group and by CYPs via oxidation reactions. The goal of this study was to establish the ...

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