Chromatin insulators are thought to restrict the action of enhancers and silencers. The best-known insulators in Drosophila require proteins such as Suppressor of Hairy wing (Su(Hw)) and Modifier of mdg4 (Mod(mdg4)) to be functional. The insulator-related proteins apparently colocalize as nuclear speckles in immunostained cells. It has been asserted that these speckles are 'insulator bodies' of...

Reactive oxygen species (ROS) contribute to the development of interstitial fibrosis and tubular atrophy seen in chronic allograft nephropathy (CAN). As molecular hydrogen gas can act as a scavenger of ROS, we tested the effect of treatment with hydrogen water (HW) in a model of kidney transplantation, in which allografts from Lewis rats were orthotopically transplanted into Brown Norway recipi...

Proof. In view of [Dou98, Proposition 3.11], it suffices to check that the supremum norm invalidates the parallelogram law. To this end, let us choose a very specific function f (x) = cos2(2πx) and g(x) = sin2(2πx). Then we have f (x) + g(x) = 1 and f (x) − g(x) = cos(4πx), hence ‖ f + g‖ = ‖ f − g‖ = 1. On the other hand, we have ‖ f ‖ = ‖g‖ = 1. Consequently ‖ f + g‖ + ‖ f − g‖ = 2 , 4 = 2‖ f...

Abstract Propensity scores represent the probability that an individual is assigned to a treatment group given the individual’s scores on a set of covariates. Propensity scores are used in nonrandomized studies to equate treatment and control groups on a large number of covariates measured at baseline. Assumptions necessary for propensity score analysis to yield a valid estimate of t...

A variety of compounds including classical anthelmintics and avermectin analogs were screened for their effects on movements of adult heartworms (HW) (Dirofilaria immitis). Contractile activity was measured by tension recording of spontaneous movements of intact HW coil preparations (6 min compound exposure) and motility was evaluated by observation of spontaneous, free movements in culture (3 ...

This study was conducted to investigate the chemical component of the hot water (HW) fraction of mycelia of Cordyceps sinensis and its antifatigue and antistress effect against a stimulus in vivo using rats and mice. The growth of mycelia reached a maximum level of 31.6 g/l after 120 h of incubation. The main chemical composition of the HW fraction of mycelia of C. sinensis was found to be carb...

Partial Runtime Reconfigurable (PRTR) FPGAs allow HW tasks to be placed and removed dynamically at runtime. We make two contributions in this paper. First, we present an efficient algorithm for finding the complete set of Maximal Empty Rectangles on a 2D PRTR FPGA. We also present a HW implementation of the algorithm with negligible runtime overhead. Second, we present an efficient online deadl...

Background: Heart failure (HF) has become one of the most prevalent cardiovascular problems worldwide. Considering the beneficial effects of probiotics on human health, we aimed to investigate the anti-inflammatory effect of oral administration of Lactobacillus paracasei in HF induced by isoproterenol. Methods: Forty Wistar male rats weighing 80g on average were randomly assigned to five grou...