نتایج جستجو برای: human leukocyte antigens

تعداد نتایج: 1737533  

Journal: :Journal of Drug Delivery and Therapeutics 2021

Major histocompatibility complex (MHC) is consisted of cluster genes known as human leukocyte antigen HLA, these are committed to process and present antigens T lymphocyte. Corona viruses, belonging a genus the corona viridae family, enveloped viruses containing single stranded RNA 27-32 kb. This study was conducted highlight some observations that may help other researcher for rapid research a...

Journal: :Journal of leukocyte biology 2003
Homayoun Shams Peter F Barnes Stephen E Weis Peter Klucar Benjamin Wizel

Mycobacterium tuberculosis antigens that are recognized by human CD8+ T cells are potentially important vaccine target molecules. We used a motif-based strategy to screen selected proteins of M. tuberculosis for peptides predicted to bind to human leukocyte antigen (HLA)-A*0201. We identified two 10 amino acid peptides that elicited cytolytic T lymphocyte activity and interferon-gamma productio...

2012
Marco Antonio Ayala García Beatriz González Yebra Andrea Liliana López Flores Eduardo Guaní Guerra

The transplant of organs is one of the greatest therapeutic achievements of the twentieth century. In organ transplantation, the adaptive immunity is considered the main response exerted to the transplanted tissue, since the principal target of the immune response is the MHC (major histocompatibility complex) molecules expressed on the surface of donor cells. However, we should not forget that ...

Journal: :Blood 1959
P LALEZARI T H SPAET

NTIGENIC DIFFERENCES among human leukocytes are well established,14 and it is known that patients can be immunized against donor leukocytes with the development of agglutinating antibodies.5 Antibodies against leukocytes have been found in patients subjected to repeated blood transfusions, and the incidence of such immunization appears to be proportional to the number of transfusions given.6’7 ...

Journal: :Cellular & molecular immunology 2007
Aifen Lin Huihui Xu Weihua Yan

Human cytomegalovirus (hCMV) has evolved multiple mechanisms to escape the host immune recognition and innate or adaptive immune responses. Among them, hCMV has developed strategies to modulate the expression and/or function of human leukocyte antigens (HLAs), including by encoding series of infection stage-dependent hCMV proteins to detain and destroy the expression of HLA molecules on the sur...

Journal: :Journal of andrology 1983
G Aumüller J Seitz W Bischof

Acid phosphatase was purified from human prostatic tissue and from seminal plasma. Antisera to antigens from both sources were raised in rabbits. These antisera have been used for immunohistochemical localization of the respective antigens in the prostates of neonatal, infantile, prepubertal, and adult individuals. Immunoreactivity of the prostatic epithelium with the seminal fluid-derived anti...

Journal: :The Medical journal of Malaysia 1990
K D Sukumaran O K Joo

The aim of this study was to determine the frequency and specificity of HLA-A and B antibodies in multiparous mothers in the Malaysian population. 1,100 maternal serum samples obtained during normal childbirth were screened against a panel of 100 lymphocytes with known HLA antigen types for HLA antibodies by the complement dependent lymphocyte microcytotoxicity dye exclusion test. From the tota...

2015
Brittany L. Shepherd Rashida Ferrand Shungu Munyati Samuel Folkard Kathryn Boyd Tsitsi Bandason Sabelle Jallow Sarah L. Rowland-Jones Louis-Marie Yindom

African infants with vertically acquired HIV infection progress rapidly, with only 50% surviving beyond 2 years in the absence of treatment. Despite this high initial mortality, recent reports describe a substantial burden of older children living with untreated vertically acquired HIV infection in Southern Africa. The immunological and genetic factors associated with long-term survival followi...

Journal: :Acta biochimica et biophysica Sinica 2011
Jianhua Hu Xueqin Meng Hong Zhao Xuan Zhang Hainv Gao Meifang Yang Yadan Ma Minhuan Li Weihang Ma Jun Fan

Human cytomegalovirus (HCMV) reactivation is a common complication after liver transplantation (LT). Here, we investigated whether human leukocyte antigen (HLA)-matching was related to HCMV infection and subsequent graft failure after LT for hepatitis B virus  cirrhosis. This retrospective study reviewed 91 LT recipients. All the patients were grouped according to HLA-A, HLA-B, and HLA-DR locus...

Journal: :Investigative ophthalmology & visual science 1980
C J Brinkman A J Pinckers R M Broekhuyse

The immune status of patients suffering from different types of retinitis pigmentosa has been investigated. The lymphocytes of these patients could be stimulated by incubation with human soluble retinal antigens as well as with bovine rod outer segments. The results suggest the involvement of the cellular immune system in retinitis pigmentosa. The leukocyte migration inhibition test also point...

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