نتایج جستجو برای: human laryngeal cancer
تعداد نتایج: 2408932 فیلتر نتایج به سال:
A parathyroid hormone-related protein (PTHrP) has recently been isolated from tumors associated with hypercalcemia. In the present study, we tested the effects of neutralizing antisera to the PTHrP on serum calcium and urine cAMP in two animal models of malignancy-associated hypercalcemia. The animal models consisted of (a) a human squamous cell lung cancer and (b) a human laryngeal cancer, bot...
Introduction For locally advanced-stage laryngeal and hypopharyngeal cancer, the total laryngectomy or laryngopharyngectomy can be an option for primary treatment. This is indicated when a partial resection not achievable while obtaining organ function preservation of its through radiotherapy possible.
BACKGROUND Analysis of the hematopoietic system has shown that bone marrow stem cells contain a subpopulation that effluxes the DNA binding dye, Hoechst 33342, out of the cell membrane. These cells are called side population (SP) cells and have been shown to have stem cell characteristics. SP cells have already been found in solid tumors, although there are no published reports examining the ro...
In a previous trial, we found that combined 13-cis-retinoic acid, IFN-alpha, and alpha-tocopherol more effectively reversed advanced premalignant lesions of the larynx than of the oral cavity and that cyclin D1 (CD1) G/A870 single nucleotide polymorphism correlated with cancer risk. We conducted the present trial primarily to confirm the clinical activity of the combination in advanced laryngea...
The melanoma differentiation-associated gene-7 [MDA-7; renamed interleukin (IL)-24] was isolated from human melanoma cells induced to terminally differentiate by treatment with interferon and mezerein. MDA-7/IL-24 functions as a multimodality anticancer agent, possessing proapoptotic, antiangiogenic and immunostimulatory properties. All these attributes make MDA-7/IL-24 an ideal candidate for c...
OBJECTIVES To provide comprehensive temporal trend analysis of 5-year relative survival rates of laryngeal cancer using the Surveillance, Epidemiology, and End Results database; and to expand on prior reports by including inclusion of laryngeal tumor location, stage, age at diagnosis, treatment strategy, and histologic grade. DESIGN Retrospective cohort analysis using the Surveillance, Epidem...
Laryngeal cancer is a malignant tumor of the head and neck with clinical features high recurrence metastasis poor prognosis. The pathogenesis laryngeal not clearly understood, but it undoubtedly complex developmental process involving multiple pathways genes. Finding new ways to treat particularly important as second most common neck, many post-operative complications, quality life outcomes for...
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