نتایج جستجو برای: human growth hormone hgh
تعداد نتایج: 2383232 فیلتر نتایج به سال:
Large cell neuroendocrine carcinoma (LCNEC) is an aggressive neoplasm with a low frequency of occurrence in the digestive tract. We present a series of eight patients diagnosed with LCNEC of the colon and rectum. Grossly, tumors were presented as endophytic/ulcerative, annular and polypoid masses, with a gray-white color and necrosis in most cases. Histologically, they were high-grade tumors co...
Human growth hormone (hGH) is a polypeptide with 191 amino acids and a molecular mass of 22 kilodaltons. With the aid of computer molecular simulation, an hGH analog was created by altering an hGH gene to reflect the change of one amino acid (glycine [G] 120 to arginine [R]) within the third alpha-helix of the hGH molecule. This hGH analog, named hGHG120R, was found to be an hGH antagonist. It ...
'25 1-human growth hormone (' 25 1-hGH) binds specifically to receptors on cultured human lymphocytes (IM-9). When this process is studied by use of quantitative EM radioau-tography, under conditions of incubation at 15 °C for 5 min, the ligand is localized to the plasma membrane of the cell. At 30 ° and 37 ° C, however, ' 25 1-hGH is progressively internalized by the cell as a function of time...
Tanner, J. M., Whitehouse, R. H., Hughes, P. C. R., and Vince, F. P. (1971). Archives of Disease in Childhood, 46, 745. Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children, with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome, and other complaints. (1) Human growth hormone (HGH) has been given for one whole year or longer to 100...
BACKGROUND The long-term safety of growth hormone treatment is uncertain. Raised risks of death and certain cancers have been reported inconsistently, based on limited data or short-term follow-up by pharmaceutical companies. PATIENTS AND METHODS The SAGhE (Safety and Appropriateness of Growth Hormone Treatments in Europe) study assembled cohorts of patients treated in childhood with recombin...
OBJECTIVE The aim of the study was to increase the number of human islet beta-cells after transplantation with injections of human growth hormone (hGH). INTERVENTIONS Human islets and fetal rat islets were transplanted under the left kidney capsule and under the right kidney capsule, respectively in nude normoglycemic mice which were then given a daily injection of 200 microg hGH for 1-4 week...
Human Growth Hormone-Releasing Hormone (hGH-RH; hGRF) Treatment of Four Patients with GH Deficiency.
This study aims to demonstrate the quantification of peptides based on isotope dilution surface enhanced Raman scattering (IDSERS). SERS spectra of phenylalanine (Phe), leucine (Leu) and two peptide sequences TGQIFK (T13) and YSFLQNPQTSLCFSESIPTPSNR (T6) as part of the 22-kDa human growth hormone (hGH) were obtained on Ag-nanoparticle covered substrates. On the basis of the dominant Phe and Leu...
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