نتایج جستجو برای: human genome project

تعداد نتایج: 2031284  

Journal: :Journal of the American Medical Informatics Association : JAMIA 2004
Joyce A. Mitchell Jane Fun Alexa T. McCray

The authors have developed the Genetics Home Reference, a consumer resource that addresses the health implications of the Human Genome Project. The research results made possible by the Human Genome Project are being made available increasingly in scientific databases on the Internet, but, because of the often highly technical nature of these databases, they are not readily accessible to the la...

Journal: :Current Biology 2001
Stephen W Scherer Joseph Cheung

Genomes: Much heat has been generated in discussions about the key human genome sequence databases, generated by the Human Genome Project and Celera, and what specific features each offers genome researchers. Stephen W. Scherer and Joseph Cheung, who are intense users of both, offer a personal assessment of the developing contents.

Journal: :Genome research 2009
Jinchuan Xing Yuhua Zhang Kyudong Han Abdel Halim Salem Shurjo K Sen Chad D Huff Qiong Zhou Ewen F Kirkness Samuel Levy Mark A Batzer Lynn B Jorde

Structural variants (SVs) are common in the human genome. Because approximately half of the human genome consists of repetitive, transposable DNA sequences, it is plausible that these elements play an important role in generating SVs in humans. Sequencing of the diploid genome of one individual human (HuRef) affords us the opportunity to assess, for the first time, the impact of mobile elements...

Journal: :The Yale Journal of Biology and Medicine 1990
David J. Eisenman

This publication presents the proceedings of the Science Writers Workshop, sponsored by the Department of Energy (DOE) as part of the Human Genome Initiative. The participants included scientists from industry, academia, and several national research laboratories in the United States as well as scientists from around the world. It consists of short individual papers summarizing a particular top...

2006
Ernest Rossi Kathryn Rossi Mauro Cozzolino Salvatore Iannotti Ernest L. Rossi

We outline our expectations for a new bioinformatic and neuroscience of therapeutic hypnosis, psychotherapy, and rehabilitation based on the Human Genome Project. Just as The Human Genome Project identified the psychobiological foundations of modern medicine with the new technology of sequencing DNA during the past decade, we propose extending this bioinformatic knowledge base with the technolo...

Journal: :Assia--Jewish medical ethics 1998
Mordechai Halperin

The Human Genome Project Science in the twentieth century has launched three great projects: (1) the Manhattan Project for the development of nuclear weapons, which took place in the United States between 1942 and 1945 under the technical supervision of Robert Oppenheimer; (2) the American Space Project, which started in the late 1950’s and led to the landing on the moon in 1968; and (3) the Hu...

Journal: :Nucleic acids research 1992
Kenneth H. Fasman Stanley Letovsky Peter W. D. Li Robert W. Cottingham David T. Kingsbury

The value of the Genome Database (GDB) for the human genome research community has been greatly increased since the release of version 6. 0 last year. Thanks to the introduction of significant technical improvements, GDB has seen dramatic growth in the type and volume of information stored in the database. This article summarizes the types of data that are now available in the Genome Database, ...

Journal: :Human mutation 2009
Jim Kaput Richard G H Cotton Lauren Hardman Michael Watson Aida I Al Aqeel Jumana Y Al-Aama Fahd Al-Mulla Santos Alonso Stefan Aretz Arleen D Auerbach Bharati Bapat Inge T Bernstein Jong Bhak Stacey L Bleoo Helmut Blöcker Steven E Brenner John Burn Mariona Bustamante Rita Calzone Anne Cambon-Thomsen Michele Cargill Paola Carrera Lawrence Cavedon Yoon Shin Cho Yeun-Jun Chung Mireille Claustres Garry Cutting Raymond Dalgleish Johan T den Dunnen Carlos Díaz Steven Dobrowolski M Rosário N dos Santos Rosemary Ekong Simon B Flanagan Paul Flicek Yoichi Furukawa Maurizio Genuardi Ho Ghang Maria V Golubenko Marc S Greenblatt Ada Hamosh John M Hancock Ross Hardison Terence M Harrison Robert Hoffmann Rania Horaitis Heather J Howard Carol Isaacson Barash Neskuts Izagirre Jongsun Jung Toshio Kojima Sandrine Laradi Yeon-Su Lee Jong-Young Lee Vera L Gil-da-Silva-Lopes Finlay A Macrae Donna Maglott Makia J Marafie Steven G E Marsh Yoichi Matsubara Ludwine M Messiaen Gabriela Möslein Mihai G Netea Melissa L Norton Peter J Oefner William S Oetting James C O'Leary Ana Maria Oller de Ramirez Mark H Paalman Jillian Parboosingh George P Patrinos Giuditta Perozzi Ian R Phillips Sue Povey Suyash Prasad Ming Qi David J Quin Rajkumar S Ramesar C Sue Richards Judith Savige Dagmar G Scheible Rodney J Scott Daniela Seminara Elizabeth A Shephard Rolf H Sijmons Timothy D Smith María-Jesús Sobrido Toshihiro Tanaka Sean V Tavtigian Graham R Taylor Jon Teague Thoralf Töpel Mollie Ullman-Cullere Joji Utsunomiya Henk J van Kranen Mauno Vihinen Elizabeth Webb Thomas K Weber Meredith Yeager Young I Yeom Seon-Hee Yim Hyang-Sook Yoo

The remarkable progress in characterizing the human genome sequence, exemplified by the Human Genome Project and the HapMap Consortium, has led to the perception that knowledge and the tools (e.g., microarrays) are sufficient for many if not most biomedical research efforts. A large amount of data from diverse studies proves this perception inaccurate at best, and at worst, an impediment for fu...

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