Introduction: Drugs are mainly delivered to the target tissues by plasma proteins, such as human serum albumin, in the human body. Practical information about the thermodynamic parameters of drugs and their stability can be obtained using simulation methods, such as molecular docking. Material & Methods: This study, investigated the molecular docking of human serum albumin with fluorouracil an...

ecological changes resulting from climate conditions can severely affect human societies especially in the area of economy and safety. climate catastrophes may cause social and economic tension. forecasting such changes accurately can help the government to control the disasters and to achieve possible benefits (such as water supply in flood). weather forecasting is the application of science a...

the paper examines for the first time the foreign exchange intervention policy in foreign exchange market of iran. and in this framework, the study designs and simulates the foreign exchange intervention model in iran. in the first section, the paper shows that the injection of oil revenues directly to economy and also the absence of potent structure of output are inclusively caused the central...

The Stueckelberg model for massive vector fields is cast into a BRS invariant, polynomial form. Its symmetry algebra simplifies to an abelian gauge symmetry which is sufficient to decouple the negative norm states. The propagators fall off like 1/k2 and the Lagrangean is polynomial but it is not powercounting renormalizable due to derivative couplings. ∗)To appear in the Proceedings of the 30th...

This article explores an alternative state space representation for ARIMA models to that usually advocated. The alternative representation has minimal state order. More importantly, it has more convenient Kalman filter convergence properties. This convergence reveals the concrete connection between classical infinite sample representations based on lag polynomials and the recursive Kalman filte...

The research presented in this thesis addresses the problem of updating an analytical model using a parametric Reference Basis approach. In this method, some parameters are assumed to be accurate (e.g. natural frequencies, mode shapes and mass matrix), while others are adjusted so that the eigenvalue equation is satisfied. Updating is done with the use of principal submatrices, and the method s...

We isolated renin granules from cadaver kidneys using discontinuous sucrose density gradient centrifugation, and investigated the storage form of the renin from these granules. Approximately 23% of the total renin activity in the original homogenate was obtained from the surface phase between 1.6 and 1.7 M sucrose (Fraction 6). Granule renin extracted from the granules in Fraction 6 was separat...

We report the results of a very high statistics Monte Carlo study of the continuum limit of the two dimensional O(3) non-linear σ model. We find a significant discrepancy between the continuum extrapolation of our data and the form factor prediction of Balog and Niedermaier, inspired by the Zamolodchikovs’ S-matrix ansatz. On the other hand our results for the O(3) and the dodecahedron model ar...

available online at http://meteoritics.org 1331 © Meteoritical Society, 2003. Printed in USA. A laboratory model of splash-form tektites Linda T. ELKINS-TANTON,1, 2* Pascale AUSSILLOUS,3 José BICO,4 David QUÉRÉ,3 and John W. M. BUSH5 1Department of Geological Sciences, Brown University, Providence, Rhode Island 02912, USA 2Department of Earth and Planetary Science, Massachusetts Institute of Te...