A longstanding controversy in paleoanthropology surrounds the question of whether Neandertals shared the prolonged growth periods of modern humans. To address this question, this investigation compares the duration of enamel formation in Neandertals with that of three comparative modern human groups. Because dental and somatic growth are correlated with each other, dental growth periods are ind...

The aim of the present study was to investigate the abrasive effect of CaCO3 and SiO2-based fluoride-free experimental toothpastes on eroded human permanent dental enamel and evaluate the effectiveness of waiting periods between acid exposure and tooth brushing. Twelve volunteers wore palatal appliances containing human enamel blocks for two periods of five days each. The appliances were immers...

ó Over sixty years of research and recent systematic reviews have shown that water fluoridation is an effective and efficient public health measure for the prevention of dental decay. ó Water fluoridation is particularly appropriate for populations demonstrating moderate to high risk of dental decay. ó At the fluoride concentrations recommended for the prevention of dental decay, human health i...

In the developing tooth, 1-hydroxyethylidene-1,1-bisphosphonate (HEBP) causes hypoplasia and hypomineralization of enamel and dentine. The present study was undertaken to clarify the effects of HEBP on the formation of dental tissues of tooth germs in an organ culture system. Mandibular first molars from 17.5-day-old mouse embryos were cultured with or without 250 microM HEBP in culture medium....

Periodontitis is primarily a dental plaque induced inflammatory disease. Anatomic factors such as cervical enamel projections, enamel pearls, and developmental grooves are often associated with advanced, localized periodontal destruction. Enamel projections and pearls are mostly associated with molars. Enamel projections in the furcation areas of molars have no true attachment and are therefore...

background and purpose: fluoride is a natural element essential for human nutrition due to its benefits for dental enamel. it is well-documented that standard amounts of fluoride in drinkingwater can decrease the rate of dental caries. this study was conducted with the aim of measuring fluoride concentration of drinking-water supplies and urban distribution system in qom, iran. materials and me...

Dihydropyrimidinase-related protein 4 (Dpysl4) is a known regulator of hippocampal neuron development. Here, we report that Dpysl4 is involved in growth regulation, polarization and differentiation of dental epithelial cells during tooth germ morphogenesis. A reduction in Dpysl4 gene expression in the tooth germ produced a loss of ameloblasts, resulting in the decrease of synthesis and secretio...

Tooth formation begins with the bud stage during which the dental lamina (derived from epithelial tissue) produces a series of tooth buds along its buccal margin. This is followed by the cap stage in which a coned structure, termed the enamel organ, is formed by an invagination of mesenchymal tissue into the tooth bud. All deciduous teeth and permanent molars are derived from the enamel organ o...

Gradual wear of opposing teeth is a normal phenomenon in human dentition. To ensure a better quality of life through better dental health, there is a need for quality dental restorative materials to repair or replace natural teeth. Several aspects are looked at when designing a proper dental implant. Aesthetics, durability, and integration with the supporting teeth and soft tissues are some key...

Enamel microabrasion has become accepted as a conservative, nonrestorative method of removing intrinsic and superficial dysmineralization defects from dental fluorosis, restoring esthetics with minimal loss of enamel. However, it can be difficult to determine if restoration is necessary in dental fluorosis, because the lesion depth is often not easily recognized. This case report presents a met...