human chromosomes

We have introduced a 6.5 Mb human mini-chromosome with a complex centromere structure into DT40 cells and have used sequence targeting and telomere-directed chromosome breakage to dissect the sequence requirements for centromere function. These experiments proved that a vertebrate centromere with two blocks of functional alphoid DNA separated by 2.5 Mb can exist as a stable structure in some bu...

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Human Bone Marrow Chromosomes in Megaloblastic Anemia

2005

Alma Irene MacLeod

T HE PROFOUND alteration in human erythrobbasts in folic acid or vitamm B12 deficiency is manifest to an important degree by the appearance of the interphase nuclear chromatin in the megaloblastic cells. This is reflected in the appearance of the individual chromosomes, and it is generally agreed that the chromosomes of megaloblasts differ in morphologic details from those of normoblasts. Rohrt...

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the salivary gland chromosomes of culex pipiens molestus

Journal: :iranian journal of public health 0

j.d. amirkhanian

the polygene chromosomal pattern together with the somatic and meiotic chromosomes of the autogenous tehran strain of culex pipiens molestus is described. the first and third chromosomes are metacentric, the second one is slightly submetacentric. each chromosome has well-defined, large puffed characteristic centromeres. randomly distributed asynaptic regions on the polytens chromosomes are ind...

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