نتایج جستجو برای: human bone marrow mesenchymal stem cells
تعداد نتایج: 2940962 فیلتر نتایج به سال:
The aim of this study was to the effect of aquatic activity and alogenic bone marrow derived mesenchymal stem cells fortified with Platelet-Rich Plasma in treatment of Achilles tendon in rat. 74 Sprague-Dawley rats were selected and tendon injury was formed in 69 of them. Subsequently, these rats were randomly divided into 8 groups and 5 rats which were without any injuries were chosen as the ...
Background: Mesenchymal stem cells (MSCs) are important candidates for MSC-based cellular therapy. Current paradigm states that MSCs support local progenitor cells in damaged tissue through paracrine signaling. Therefore, study of paracrine effects and secretome of MSCs could lead to the appreciation of mechanisms and molecules associated with the therapeutic effects of these cells. This study ...
low-intensity laser therapy (lilt) is defined to supply direct biostimulative light energy to the cells. while several studies have demonstrated that lilt has stimulating effects on bone cells and can accelerate the repair process of the bone, others reported delayed fracture healing or no effects after lilt. the aim of this article was to review the studies evaluating the biomodulation effects...
The stem cells that maintain and repair the postnatal skeleton remain undefined. One model suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, chondrocytes, marrow stromal cells, and adipocytes, although the existence of these cells has not been proven through fate-mapping experiments. We demonstrate here that expression of the bone morphogenetic protein (BMP) a...
Purpose: The aim of this study is to evaluate the effects of prepared serum from rat peripheral blood on growth and viability of rat bone marrow-derived mesenchymal stem cells (MSCs) in vitro. Materials and Methods: Bone marrow cells prepared from rat’s tibia and femur central canal were cultured either in medium containing fetal bovin serum (FBS) or rat peripheral blood-derived serum (PBDS) f...
stem cells are self-renewing cells that can be differentiated into other cell types. conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2d) cultures. the design of three-dimensional (3d) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...
PURPOSE Mesenchymal stem cells (MSC) are self-renewing, multipotent cells that are present in many adult tissues, including bone marrow, trabecular bone, adipose, and muscle. The presence of such cells of mesenchymal origin and their role during the wound healing of ocular injuries are currently being explored by many studies worldwide. In this study, we aimed to report the presence of mesenchy...
Multipotent adult progenitor cells (MAPCs) are bone marrow-derived stem cells that have extensive in vitro expansion capacity and can differentiate in vivo and in vitro into tissue cells of all 3 germinal layers: ectoderm, mesoderm, and endoderm. The origin of MAPCs within bone marrow is unknown. MAPCs are believed to be derived from the bone marrow stroma compartment as they are isolated withi...
Background and Objective: Nowadays, mesenchymal stem cells (MSCs) are considered as a promising tool for treatment of different diseases. Due to the low frequency of MSCs, however, it seems inevitable to expand them in vitro prior to use, which could affect the quality of the cells. In all isolation procedures, the density gradient separation of Ficoll is used for volume reduction and RBC exclu...
brain injuries that caused by strokes (result of intra partum ischemia) are a frequent cause of prenatal mortality and morbidity with limited therapeutic options. transplanting human mesenchymal stem cells (hmscs) indicates improvement in hypoxic ischemic brain injury (hibd) by secretion growth factor stimulating repair processes (hmscs) known as multi potent cells which isolated from bone marr...
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