نتایج جستجو برای: hsil

تعداد نتایج: 584  

2016
R. Landy A. Castanon W. Hamilton A. W. W. Lim N. Dudding A. Hollingworth P. D. Sasieni

OBJECTIVE To assess the sensitivity, the number needed to screen (NNS) and the positive predictive value (PPV) of cervical cytology for the diagnosis of cancer by age in a screening population. METHODS A retrospective cohort of women with invasive cervical cancer nested within a census of cervical cytology. All (c. 8 million) women aged 20-64 years with cervical cytology (excluding tests afte...

Journal: :Indian Journal of Public Health Research and Development 2023

Background: Cervical PAP smear examinationis an idealinvestigationfor early detection of benign and malignant conditions uterus because cervical infections are commonly encountered problems in women during their reproductive age some cases post-menopausal.Method: Out 3980 female patients aged between 21 to 80 years 3910 (98.2%) had pathological significance. were prepared by using disposable ay...

Journal: :Marmara Medical Journal 2021

Objective: The high number of smear tests has a workload on pathologists/cytopathologists, which raises the concern for quality diagnoses. application high-risk human papillomavirus (hr-HPV) analyses with PAP begun to contribute clinical practice. In this study, we aimed show effect hr-HPV analysis results via atypical squamous cell/squamous intraepithelial lesion (ASC/SIL) ratio standards. Mat...

Journal: :Gynecologic Oncology 2021

Background: With the implementation of primary high-risk human papillomavirus (hrHPV) screening in Netherlands, an increase was observed number unnecessary referrals (?Cervical Intraepithelial Neoplasia (CIN) 1) to colposcopy. We aimed investigate which alternative triage strategies safely reduce HPV-based cervical cancer programmes. Methods: Microsimulation model MISCAN used simulate unvaccina...

Journal: :Indian Journal of Pathology and Oncology 2022

: The Papanicolaou (Pap) smear used worldwide for cervical screening was developed by Dr George in 1940s. Pap is a simple, safe and effective test to detect cancer at an early stage. To study the spectrum of lesions based on Bethesda System(TBS) 2014 determine frequency premalignant malignant lesions. present prospective included 200 cases above 20 years age. cytological interpretation smears w...

2016

The high sensitivity of the diagnostic procedures now available in cervical cancer screening, as liquid-based cytology, permits to diagnose an ever greater number of preinvasive lesions of the cervix (High Grade Squamous Intraepithelial Lesions HSIL). The increasing number of women in reproductive age presenting these lesions requires a conservative approach. The surgical technique of large-loo...

Journal: :Sao Paulo medical journal = Revista paulista de medicina 2003
Ledy do Horto dos Santos Oliveira Eliane de Vasconcelos Machado Rodrigues Ana Paula Terra Alvim de Salles Lopes André de Paula Fernandez Silvia Maria Baeta Cavalcanti

CONTEXT Persistent infection with high risk human papillomavirus (HPV) has been linked to cervical carcinoma. Integration of viral DNA into host cell DNA is essential for this cancer development, promoting disruption of the HPV E2 gene, thus leading to unregulated increases in E6 and E7 proteins and inactivating the products of p53 and Rb tumor suppressor genes. OBJECTIVE To investigate HPV 1...

2011
Vinod B. Shidham Ravi Mehrotra George Varsegi Krista L. D'Amore Bryan Hunt Raj Narayan

BACKGROUND p16 (INK4a) (p16) is a well-recognized surrogate molecular marker for human papilloma virus (HPV) related squamous dysplasia. Our hypothesis is that the invasive interventions and related morbidities could be avoided by objective stratification of positive cytologic interpretations by p16 immunostaining of cell block sections of cytology specimens. MATERIALS AND METHODS Nuclear imm...

2011
Ana Mitrović-Jovanović Branko Stanimirović Branka Nikolić Snežana Pantić-Aksentijevic

Cervical intraepithelial neoplasms The cervical intraepithelial neoplasms (CINs) are abnormalities of the squamous ectocervical epithelium. The first group consists of squamous intraepithelial lesions of low histological stage (LSIL) and includes flat condyloma and CIN I, while the second group consists of squamous intraepithelial lesions of high histological stage (HSIL) including CIN II and C...

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