OBJECTIVE Despite the clinical importance of an accurate diagnosis in individuals with monogenic forms of diabetes, restricted access to genetic testing leaves many patients with undiagnosed diabetes. Recently, common variation near the HNF1 homeobox A (HNF1A) gene was shown to influence C-reactive protein levels in healthy adults. We hypothesized that serum levels of high-sensitivity C-reactiv...

AIMS High sensitive-C-reactive protein (hs-CRP) is associated with coronary risk, which may be explained by an association with (unstable) coronary artery disease (CAD). Until now, histopathological and angiographic studies have failed to consistently demonstrate a strong relationship. However, most of these studies were limited by a cross-sectional design. Our aim was to prospectively evaluate...

AIM It is important to explore predictive markers other than conventional cardiovascular risk factors for early detection and treatment of chronic kidney disease (CKD), a major risk factor for end-stage renal failure. We hypothesized that serum albumin and high-sensitivity C-reactive protein (hs-CRP) to be independent markers, and examined their associations with the risk of CKD. METHODS We e...

background: some patients with gdm (gestational diabetes mellitus) still experience impaired glucose tolerance after childbirth and will be affected by diabetes mellitus type 2. objectives: the aim of this study is to investigate the relationship between hs-crp serum levels with insulin resistance six weeks after childbirth in patients with gestational diabetes mellitus type 2. methods: in this...

Inflammation appears to be an integral part of the process of atherosclerosis that leads to coronary artery disease (CAD) and acute ischemic syndromes (1, 2). Data indicate that high-sensitivity C-reactive protein (hs-CRP) and other inflammatory markers are associated with atherosclerosis and that hs-CRP decreases with statin treatment (3, 4). These are important findings that support the infla...

BACKGROUND & OBJECTIVES Elevated levels of c-reactive protein (CRP) are known to be associated with insulin resistance and metabolic syndrome in adults. A substantial prevalence of hyperinsulinaemia and elevated CRP levels have been shown in Indian young adults. We therefore studied the association of serum high-sensitivity C-reactive protein (hs-CRP) with fasting insulin and insulin resistance...

background and objective: the aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-crp) in preeclampsia and to compare hs-crp levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. materials and methods: serum hs-crp levels were investigated in 40 cases of normal pregnant women, 37 cases with mild preeclampsia and 38 cases...

conclusions we found that the use of clopidogrel in patients undergoing pci had favorable effects on the suppression of hs-crp. this effect appears to be heightened and more apparent in some group of patients with co-morbidities such as diabetes and hypertension. results six hundred-fifty patients including 386 (59.4%) male and 264 (40.6%) female subjects were enrolled in the study. the mean hs...

Type 2 diabetes mellitus is associated with increased cardiovascular risk. Two markers of cardiovascular risk assessment are high sensitivity Creactive protein (hs-CRP) and non-high density lipoprotein cholesterol (non-HDL cholesterol). This case-control study attempted to compare levels of hs-CRP and non-HDL cholesterol between type 2 diabetic patients and non-diabetic individuals and investig...