نتایج جستجو برای: hotspots analysis
تعداد نتایج: 2829828 فیلتر نتایج به سال:
BACKGROUND Malaria transmission is highly heterogeneous in most settings, resulting in the formation of recognizable malaria hotspots. Targeting these hotspots might represent a highly efficacious way of controlling or eliminating malaria if the hotspots fuel malaria transmission to the wider community. METHODS/DESIGN Hotspots of malaria will be determined based on spatial patterns in age-adj...
Repair of DNA lesions must occur within the chromatin landscape and is associated with alterations in histone modifications and nucleosome rearrangement. To directly associate these chromatin features with DNA damage and repair, it is necessary to be able to map DNA adducts. We have developed a cyclobutane pyrimidine dimer (CPD)-specific immunoprecipitation method and mapped ultraviolet damage ...
Identification of invasion hotspots that support multiple invasive alien species (IAS) is a pre-requisite for control and management of invasion. However, till recently it remained a methodological challenge to precisely determine such invasive hotspots. We identified the hotspots of alien species invasion in India through Ecological Niche Modelling (ENM) using species occurrence data from the ...
Meiotic recombination is the most important source of genetic variation in higher eukaryotes. It is initiated by formation of double-strand breaks (DSBs) in chromosomal DNA in early meiotic prophase. The DSBs are subsequently repaired, resulting in crossovers (COs) and noncrossovers (NCOs). Recombination events are not distributed evenly along chromosomes but cluster at recombination hotspots. ...
Human activity hotspots are the clusters of activity locations in space and time, and a better understanding of their functionality would be useful for urban land use planning and transportation. In this article, using trajectory data, we aim to infer the functionality of human activity hotspots from their scaling pattern in a reliable way. Specifically, a large number of stopping locations are...
Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa
BACKGROUND Malaria transmission intensity is heterogeneous, complicating the implementation of malaria control interventions. We provide a description of the spatial micro-epidemiology of symptomatic malaria and asymptomatic parasitaemia in multiple sites. METHODS We assembled data from 19 studies conducted between 1996 and 2015 in seven countries of sub-Saharan Africa with homestead-level ge...
This study identified high-risk locations (hotspots) using geographic information systems (GIS) and spatial analysis. Five years of accident data (2013–2017) for the Lokoja-Abuja-Kaduna highway in Nigeria were used. The concentration analysis was conducted mean center Kernel density estimation method. These further verified Moran’s I statistics (spatial autocorrelation) to determine their clust...
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