Of 71 acute lymphoblastic leukemia survivors at our hospital over the past 10 years, 2 children developed mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). This is the first report to describe the clinical course of MTLE-HS observed longitudinally by EEG and MRI. Patient 1 experienced a seizure during chemotherapy involving intrathecal methotrexate. Postseizure MRI suggested m...

POLYMERIC OSTEOPONTIN EMPLOYS INTEGRIN α9β1 AS A RECEPTOR AND ATTRACTS NEUTROPHILS BY PRESENTING A DE NOVO BINDING SITE* Norihisa Nishimichi, Fumiko Higashikawa, Hiromi H. Kinoh, Yoshiko Tateishi, Haruo Matsuda, & Yasuyuki Yokosaki From Cell-Matrix Frontier Laboratory, Biomedical Research Unit, Hiroshima University, 1-2-3 Kasumi, Minamiku, Hiroshima, 734-8551; Laboratory of Immunobiology, Depar...

Hiroki Shiomi, M.D., Takeshi Morimoto, M.D, PhD., Shoji Kitaguchi, M.D., Yoshihisa Nakagawa, M.D., Katsuhisa Ishii, M.D., Yoshisumi Haruna, M.D, PhD, Itaru Takamisawa, M.D., Makoto Motooka, M.D., Kazuhiro Nakao, M.D., Shintaro Matsuda, M.D., Satoru Mimoto, M.D., Yutaka Aoyama, M.D., Teruki Takeda, M.D., Koichiro Murata, M.D., Masaharu Akao, M.D., Tsukasa Inada, M.D., Hiroshi Eizawa, M.D., Eiji ...

the fact that the properties of a molecule are tightly connected to its structural  characteristics  is one of the fundamental concepts in chemistry. in this connection,  graph theory has been successfully applied in developing some relationships between topological indices and some thermodynamic properties. so ,  a novel method for computing the new descriptors to construct a quantitative rela...

Common ash ( Fraxinus excelsior L.) is a keystone tree species in Europe. However, since the 1990s, this has been experiencing widespread decline and mortality due to dieback [ Hymenoscyphus fraxineus (T. Kowalski) Baral, Queloz Hosoya]. Besides H. , emerald borer Agrilus planipennis Fairmaire), an invasive alien pest already devastating trees western Russia, spreading westward becoming emergin...

The fact that the properties of a molecule are tightly connected to its structural  characteristics  is one of the fundamental concepts in chemistry. In this connection,  graph theory has been successfully applied in developing some relationships between topological indices and some thermodynamic properties. So ,  a novel method for computing the new descriptors to construct a quantitative rela...

The interaction of a series of derivatives of tyrosine with horseradish peroxidase (HRP) and lactoperoxidase (LPO) was studied by using optical difference spectroscopy, c.d. and proton n.m.r. spectroscopy in order to reveal differences in the mode of binding of L-tyrosine and D-tyrosine, which are substrates of but react at different rates with the two peroxidases, to HRP and LPO. All the donor...

RUN, Xtatic, RUN: EFFICIENT IMPLEMENTATION OF AN OBJECT-ORIENTED LANGUAGE WITH REGULAR PATTERN MATCHING Michael Y. Levin Benjamin C. Pierce Schema languages such as DTD, XML Schema, and Relax NG have been steadily growing in importance in the XML community. A schema language provides a mechanism for defining the type of XML documents; i.e., the set of constraints that specify the structure of X...

Phosphorylation on Ser 19 of the myosin II regulatory light chain by myosin light chain kinase (MLCK) regulates actomyosin contractility in smooth muscle and vertebrate nonmuscle cells. The smooth/nonmuscle MLCK gene locus produces two kinases, a high molecular weight isoform (long MLCK) and a low molecular weight isoform (short MLCK), that are differentially expressed in smooth and nonmuscle t...