OBJECTIVE There is some evidence that use of hormonal contraceptives, particularly the more androgenic formulations, can alter a woman's glucose tolerance. We examined the association between hormonal contraceptive use, categorized by the androgenicity of the progestin component, and risk of gestational diabetes mellitus (GDM) in a nested case-control study. RESEARCH DESIGN AND METHODS Case (...

PURPOSE OF REVIEW As the length of survival in patients with gynecological malignancies increases due to advances in early diagnosis and therapy, quality of life becomes a major issue for the survivors. These women frequently suffer symptoms following an iatrogenically induced menopause. Many gynecologists advise these patients against hormonal replacement therapy. This review attempts to provi...

It is well known that nutrient availability controls plant development. Moreover, plant development is finely tuned by a myriad of hormonal signals. Thus, it is not surprising to see increasing evidence of coordination between nutritional and hormonal signaling. In this opinion article, we discuss how nitrogen signals control the hormonal status of plants and how hormonal signals interplay with...

Hormonal therapy and the humanised anti-HER2 monoclonal antibody trastuzumab (Herceptin) represent one of the oldest and one of the newest treatment modalities for breast cancer, respectively. Recent data have suggested that HER2 overexpression is associated with resistance to hormonal therapy and there is considerable preclinical evidence to support the existence of interaction or 'cross talk'...

Although epidemiologic studies, animal experiments and receptor studies have shown that not only normal ovaries but also many malignant ovarian tumors can be considered as endocrine related and hormone dependent, the place of hormonal therapy in the management of patients with ovarian cancer remains unsettled. Most trials of hormonal treatment in ovarian cancer have been retrospective, involved...

Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases ...

Gynecologic cancers are malignancies that affect the female organs of reproduction and the genitalia. Collectively, these cancers comprise approximately 13% of cancers in women (Jemal et al., 2006; Martin, 2004). Screening has been particularly benefi cial in reducing mortality in cervical cancer. However, an effective screening tool for other gynecologic cancers remains elusive and cost prohib...

An increasing amount of research has shown a relationship between hormonal exposure and functional lateralisation. In this study different sources of hormonal exposure were examined: prenatal exposure, estimated using the 2D:4D ratio, and later life exposure through examining the effects of hormone replacement therapy. In addition to considering multiple sources of hormonal exposure, three test...

INTRODUCTION Hormonal contraceptives can influence female sexual function. AIM The goal of this article was to provide a comprehensive review of the effects that various hormonal contraceptives may have on female sexual function. METHODS A Medline search was conducted using several terms related to and including the terms contraception, oral contraceptive, female sexual function, dyspareuni...

Women who are regularly cycling exhibit different partner preferences than those who use hormonal contraception. Preliminary evidence appears to suggest that during pregnancy women's partner preferences also diverge from those prevalent while regularly cycling. This is consistent with the general assertion that women's mate preferences are impacted by hormonal variation. During pregnancy, women...