Holt Oram Syndrome (HOS) falls in rare prevalence category with probability of 0.7 100,000 live births. It is a autosomal dominant multiple malformation syndrome characterized by abnormalities affecting hands, wrists, arms,congenital heart defects and/or conduction problems. Genetic mutations observed TBX5 gene attributed as the main cause HOS. Our patient his late 40s was diagnosed Syndrome. H...

In this paper, we evaluate the capability to detect traffic anomalieswith Shewhart, CUSUM, andEWMA control charts. In order to cope with seasonal variation and serial correlation, control charts are not applied to traffic measurement time-series directly, but to the prediction errors of exponential smoothing and Holt-Winters forecasting. The evaluation relies on flow data collected in an ISP ba...

Abstract In this study, the data at Idenak hydrometric station were used to predict inflow Maroun Dam reservoir. For purpose, different models such as artificial intelligence, Holt-Winters and hybrid used. Partial mutual information algorithm was determine input parameters affecting modeling monthly by intelligence models. According Hempel Akaike criterion, we introduced with a 3-month lag, tem...

Already Hermann Grassmann’s father Justus (1829, 1830) published two works on the geometrical description of crystals, influenced by the earlier works of C.S. Weiss (1780-1856) on three main crystal forces governing crystal formation. In his 1840 essay on the derivation of crystal shapes from the general law of crystal formation Hermann established the notion of a three-dimensional vectorial sy...

Entanglement in quantum mechanics contradicts local realism and is a manifestation of quantum nonlocality. Its presence can be detected through the violation of Bell, or Clauser-Horne-Shimony-Holt (CHSH) inequalities. Paradigmatic quantum systems provide examples of both, nonentangled and entangled states. Here, we consider a minimal complexity setup consisting of six Majorana zero modes. We fi...

The problem of medium to long term sales forecasting raises a number of requirements that must be suitably addressed in the design of the employed forecasting methods. These include long forecasting horizons (up to 52 periods ahead), a high number of quantities to be forecasted, which limits the possibility of human intervention, as well as frequent introduction of new articles (for which no pa...

Holt-Oram syndrome (HOS) is a developmental disorder inherited in an autosomal-dominant pattern. Affected organs are the heart and forelimbs with upper extremity skeletal defects and congenital heart malformation. In this study we present three cases of HOS in the same family. In one of these three individuals we detected a transition of C to T (CTG-GTT, V205V) in exon 7 of the TBX5 gene. This ...