The burden of cancer is growing globally and is one of the top leading causes of death. Information on cancer patterns are essential for effective planning of cancer control interventions. There is limited published information available on pattern of cancer for the state of Odisha, India. The present study was an attempt to explore the pattern and trend of cancer in Odisha. To fulfill the obje...

BACKGROUND Primary testicular lymphoma is a unique, rare and aggressive extra nodal non-Hodgkins Lymphoma (NHL). It is the most common testicular tumour in males between 60 and 80 years old OBJECTIVE To report a case of primary testicular lymphoma in a young man who has done very well on surgery and chemotherapy. METHODS The patient a Nigerian male civil servant who was single and aged 31 y...

By H. BRAUNSTEINER, K. FELLINGER AND F. PAKESCH D URING the last years, electron microscopic studies of leukemic tissues in chicken and mice have revealed the presence of intraand extracellularly located virus-like bodies.14 The bodies are very similar to those found in solid tumors of animals, such as Rous’ sarcomas or breast carcinomas.2’3 Some particles were also found in animals without evi...

nonexposed colleagues, and that uncorrected number was statistically signifi cant. Elevated rates emerged for prostate and thyroid cancer, melanoma, non-Hodgkins lymphoma, multiple myeloma, and leukemia. With the prevalence of cancer in the general population, at least some of the increases were probably an artifact of the intensifi ed screenings that 9/11 fi rst responders in the study receive...

Chlorophenoxy compounds, particularly 2,4-dichlorophenoxyacetic acid (2,4-D) and 4-chloro-2-methylphenoxy)acetic acid (MCPA), are amongst the most widely used herbicides in the United States for both agricultural and residential applications. Epidemiologic studies suggest that exposure to 2,4-D and MCPA may be associated with increased risk non-Hodgkins lymphoma (NHL), Hodgkin's disease (HD), l...

The ongoing JANUS project was started in 1973. The serum bank comprises 424,938 serum samples consolidated from 293,692 donors. The specimens are stored at -25 degrees C. From 1 to 13 consecutive samples are available from each donor. Up to October 1993 about 14,000 of the donors had developed some form of cancer. Frozen serum samples collected from a few months to 19 years prior to clinical re...

History of HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome), dates back to 1981 when Centre for Disease Control reported five cases of pneumocystis carinii pneumonia in homosexual men in California. A major medical crisis that has hit families, communities and nations across the world, AIDS has already caused the death of over 30 million people worldwide. Several...

Bronchial complications, including stricture, stenosis, and/or anastomotic dehiscence, are a major cause of morbidity following single lung transplantation. This report describes a 19-year-old man with a diagnosis of end-stage pulmonary fibrosis secondary to prior chemotherapy for non-Hodgkins lymphoma who underwent single lung transplantation. The immunosuppressive regimen included cyclosporin...

The clinical course of viral hepatitis can get complicated by a myriad of rheumatic symptoms which can alter the management strategies and have a profound potential to impair the quality of life of the patient. Rheumatic complications are often seen with hepatitis B (HBV) and hepatitis C (HCV) virus infections. The mechanism of these rheumatic complications seems to be immune mediated. Chronic ...

Mycosis fungoides (MF) and its leukemic variant Sézary syndrome (SS) comprise the majority of CTCL, a heterogenous group of non-Hodgkins lymphomas involving the skin. The CTCL's resistance to chemotherapy and the lack of full understanding of their pathogenesis request further investigation. With the view of a more targeted therapy, we evaluated in vitro the effectiveness of bortezomib and meth...