The relationship between hemic neoplasia, a blood cell disorder in bivalve molluscs, and chemical contaminants was evaluated in the common mussel (Mytilus edulis complex). Hemic neoplasia (HN) is endemic to mussel populations in Puget Sound. The prevalence of hemic neoplasia ranged from 0 to 30% in mussels from nine sites in Puget Sound, Washington. Organic chemical contamination in sediment fr...

Given a monotone graphical property Q, how large should d(n) be to ensure that if (Hn) is any sequence of graphs satisfying |Hn| = n and (Hn)¿d(n), then almost every induced subgraph of Hn has property Q? We prove essentially best possible results for the following monotone properties: (i) k-connected for :xed k, (ii) Hamiltonian. c © 2002 Elsevier Science B.V. All rights reserved.

HE fact that a posttreatment can abolish the mutations induced by a mutaTgenic agent can furnish a tool for the study of the metabolic conditions that are necessary for the completion of processes that begin with the mutagenic treatment and lead finally to mutation (WITKIN 1956; DOUDNEY and HAAS 1958, 1960). Different agents can produce a decrease in the mutation frequency after UV treatment: v...

It has been shown that the L289A-mutated Newcastle disease virus (NDV) fusion (F) protein gains the ability to promote fusion of Cos-7 cells independent of the viral hemagglutinin-neuraminidase (HN) protein and exhibits a 50% enhancement in HN-dependent fusion over wild-type (wt) F protein. Here, we show that HN-independent fusion by L289A-F is not exhibited in BHK cells or in several other cel...

BACKGROUND Hyperthermia is considered an efficient complement in the treatment of head and neck squamous cell carcinoma (HNSCC). Hyperthermia induces cell apoptosis in a temperature- and time-dependent manner. However, the molecular mechanism of hyperthermia remains unclear. The aim of this study was to investigate the mechanism of apoptosis induced by ultrasound hyperthermia in HNSCC cell line...

We study the interface of Ising model in a box side-length n Z3 at low temperature 1∕β under Dobrushin’s boundary conditions, conditioned to stay half-space above height −h (a hard floor). Without this conditioning, Dobrushin showed 1972 that typically most is flat 0. With floor, for small h, expected exhibit entropic repulsion, where typical lifts off Detailed understanding SOS model—a more tr...

The HN-1 module was previously reported to ensure efficient targeting of head and neck squamous cell carcinoma (HNSCC). Aim of this work was to indentify the target of HN-1. Targeting of HN-1 peptide was compared in normal epithelial cells (BEAS-2B) and in HNSCC tumor cells (SCC-25 and Detroit 562). Experimental, cell culture, cell polarity, and adhesion conditions were tested; structure models...

Paramyxovirus infects cells by initially attaching to a sialic acid-containing cellular receptor and subsequently fusing with the plasma membrane of the cells. Hemagglutinin-neuraminidase (HN) protein, which is responsible for virus attachment, interacts with the fusion protein in a virus type-specific manner to induce efficient membrane fusion. To elucidate the mechanism of HN-promoted membran...

To evaluate the contribution of length diversity in the hemagglutinin-neuraminidase (HN) protein to the pathogenicity, replication and biological characteristics of Newcastle disease virus (NDV), we used reverse genetics to generate a series of recombinant NDVs containing truncated or extended HN proteins based on an infectious clone of genotype VII NDV (SG10 strain). The mean death times and i...

For a gaussian interaction V (x, y) = λ e− x2+y2 2r2 with long range r >> lB, lB the magnetic length, we rigorously prove that the eigenvalues of the finite volume Hamiltonian HN,LL = PLLHNPLL, HN = ∑N i=1 ( −i~∇xi − eA(xi) 2 + ∑ i,j; i6=j V (xi − xj), rotA = (0, 0, B), and PLL the projection onto the lowest Landau level, are given by the following set: Let M be the number of flux quanta flowin...