We have developed a mathematical model for in-host virus dynamics that includes spatial chemotaxis and diffusion across a two-dimensional surface representing the vaginal or rectal epithelium at primary HIV infection. A linear stability analysis of the steady state solutions identified conditions for Turing instability pattern formation. We have solved the model equations numerically using para...

Persons living with human immunodeficiency virus (HIV) are living longer; therefore, they are more likely to suffer significant morbidity due to potentially treatable liver diseases. Clinical evidence suggests that the growing number of individuals living with HIV and liver disease may have a poorer health-related quality of life (HRQOL) than persons living with HIV who do not have comorbid liv...

Current arguments for the role of cofactors in the initiation of a chronic HIV infection and progression of AIDS are given. The natural history of an HIV infection as affected by cofactors which provide additional stimulatory signals is explored through a mathematical model. The model demonstrates that "antigen load" plays a role in determining susceptibility to an HIV infection. It also sugges...

conclusions although significant differences (p < 0.01) were observed in the frequency of ttmdv/sav between healthy controls and each of the hiv positive and hiv/hcv co-infected individuals, no significant difference was observed between hiv positive and hiv/hcv co-infected cases, which may be due to hiv associated immunodeficiency. this is the first time that ttmdv/sav is reported in hiv infec...

Modeling human immunodeficiency virus (HIV) via fractional operators has several benefits over the classical integer-order HIV model. The reason is that model relies not only on recent status but also former conduct of Thus, we are motivated to introduce and analyze a new This article focuses novel under proportional Hadamard-Caputo operators. study this involves existence uniqueness (EU) its s...

BACKGROUND Tools using local HIV data to help jurisdictions estimate future demand for medical and support services are needed. We present an interactive prevalence projection model using data obtainable from jurisdictional HIV surveillance and publically available data. METHODS Using viral load data from Georgia's enhanced HIV/AIDS Reporting System, state level death rates for people living ...