CONTEXT Incidence of human immunodeficiency virus (HIV) in the United States has not been directly measured. New assays that differentiate recent vs long-standing HIV infections allow improved estimation of HIV incidence. OBJECTIVE To estimate HIV incidence in the United States. DESIGN, SETTING, AND PATIENTS Remnant diagnostic serum specimens from patients 13 years or older and newly diagno...

Human immunodeficiency virus type 1 (HIV-1) can infect CD4+ lymphocytes, monocytes-macrophages, and various other cell lines, including B-cell lines. To study the parameters of B-cell infections, we examined the susceptibility of 24 B-lymphoid cell lines to both HIV-1 and HIV-2 infections. These cell lines included a series of Epstein-Barr virus (EBV) genome-negative Burkitt's lymphoma cell lin...

India has the world's second largest burden of HIV-infected persons. People with advanced stages of HIV infection are vulnerable to secondary infections and malignancies that are generally termed as opportunistic infections. A hospital based descriptive study was conducted at MNR Hospital in the department of microbiology, MNR rural medical college sangareddy dist AP. To know the prevalence of ...

This study was carried out to determine the presence of intestinal parasites and their correlation with CD4(+) T-cell counts and demographics among human immunodeficiency virus (HIV)-positive patients in Benin City, Nigeria. Stool specimens from 2,000 HIV-positive patients and 500 controls (HIV-negative individuals) were examined for ova, cysts, or parasites, using standard procedures. In addit...

evaluation of trends in the rate of infectious diseases of blood donors is essential for monitoring safety of blood supply and effective screening of donors. transfusion records of blood donors who attended the center between 2002 and 2005 were reviewed for positive cases of hbs (by elisa), hiv (by western blot) and hcv (by elisa). during 2002–05, 507,531 persons donated blood. the prevalence r...

background and objectives: hiv-1 and hcv infections are life threatening problems in patients who receive blood products. serological methods have proven useful in detecting these infections, but there are setbacks that make it challenging to detect these infectious agents. by the advent of nucleic acid testing (nat) methods, especially in multiplex format, more precise detection is possible. m...

OBJECTIVE Recent randomised clinical trials among stable HIV sero-discordant couples (SDCs) in sub-Saharan Africa (SSA) have reported that about 20-30% of new HIV infections are acquired from external sexual partners, rather than transmitted from the infected to the uninfected partner within the couple. The aim of this study is to examine whether, and to what extent, these findings are generali...

Aim: Helminth infections result from poor sanitation. We evaluated the effect of helminth on HIV disease progression through monitoring 2 outcomes: (1) plasma HIV-1 RNA Viral load (V/L) and (2) Cluster Differentiation (CD4+) T-lymphocyte count amongst helminth-HIV-1 co-infected persons. hypothesized that concurrent compromise immune control, resulting in rising VL reduced CD4+ that, subject to ...

HIV and AIDS patients are susceptible to opportunistic infections. Oral candidiasis or thrush is the primary manifestation of fungal infection in these patients. The objective this literature review was summarize established novel treatment options for oropharyngeal infections HIV/AIDS Azoles polyenes two antifungal drug classes employed oral candidiasis. A conducted on Medline Google Scholar O...

As the HIV epidemic has matured, a substantial proportion of new infections worldwide may be occurring within stable partnerships. Within the United States, blacks are disproportionately affected by HIV disease, and the drivers of this epidemic involve behavioral and structural factors. The 17th Conference on Retroviruses and Opportunistic Infections highlighted new insights into drivers of HIV...