Background : Basal cell carcinoma (BCC) is the most commonest malignant tumor of skin especially fair-skinned individuals makes up roughly 70–80% all tumors. In certainty, this malignancy had a variety many sub-types, through distinct histo-morphological appearance and biological function. Unlike other tumors, usually has an affirmative clinical course, developing slowly just locally. Antibodie...

BACKGROUND Cutaneous mast cell tumours are one of the most common neoplasms in dogs and show a highly variable biologic behaviour. Several prognosis tools have been proposed for canine mast cell tumours, including histological grading and cell proliferation markers. CD117 is a receptor tyrosine kinase thought to play a key role in human and canine mast cell neoplasms. Normal (membrane-associate...

AIM OF THE STUDY Expression of oestrogen and progesterone receptors is a very powerful and useful predictor. Because the response rate to hormonal treatment in breast cancer is associated with the presence of oestrogen and progesterone receptors, assessment of the receptor expression profile allows for prediction of breast cancer response to hormonal treatment. The aim of this study was to asse...

background: the effects of electromagnetic field (emf) on reproductive system have been of critical concern for a long time. it has been shown that the emf can adversely affect testicular cells and tissue and decrease male fertility. the most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...

Histological chorioamnionitis (HCA) is an established marker of ascending infection, a major cause of preterm birth. No studies have characterised the global change in expression of genes involved in the toll-like receptor (TLR) signalling pathways in the presence of HCA in the setting of preterm birth (pHCA). Fetal membranes were collected immediately after delivery and underwent histological ...

Indoleamine 2, 3-dioxygenase (IDO) is a rate-limiting enzyme for tryptophan metabolism inducing immune tolerance of tumors. The purpose of this study is to investigate IDO expression and its prognostic significance in bladder urothelial carcinoma (BUC). In this study, immunohistochemical staining for IDO expression in BUC tissues (n = 84) and normal bladder tissues (n = 22) was performed. The m...

BACKGROUND Nasopharyngeal carcinoma (NPC), a malignancy arising from the epithelial lining of the nasopharynx, is distinct from others cancers in terms of its epidemiologic features. It is rare in most parts of the world except for a few regions with populations of Mongoloid origin. OBJECTIVES To study the expression pattern of Epstein Barr virus (EBV) encoded oncoproteins EBNA1 and LMP1 in d...