Histiocytic necrotizing lymphadenitis (HNL; Kikuchi-Fujimoto disease) is a rare benign disorder. The diagnosis of HNL is established on recognizing the characteristic histologic findings from biopsy of the enlarged lymph nodes. Though diagnosis of HNL by fine-needle aspiration (FNA) was reported, the characteristic fine-needle aspiration cytologic features with conventional cytology and a liqui...

BACKGROUND Kikuchi-Fujimoto disease is a self-limited clinicopathologic entity that is increasingly recognized worldwide. Kikuchi-Fujimoto disease is characterized by cervical lymphadenopathy occurring in young adults. Neurologic involvement is rare, and testitis directly caused by Kikuchi-Fujimoto disease has not yet been reported. CASE PRESENTATION A 19-year-old man was brought to our clini...

Correspondence: Dr. Ram Chandra Adhikari, MD Consultant Pathologist, Department of Pathology, Om Hospital & Research Centre, Kathmandu, Nepal GPO Box: 2496 E-mail: [email protected] Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a benign, self limited condition with higher prevalence among Japanese and other Asiatic people. Though the cause of this disease remains unc...

Understanding the origins, treatment, prevention, and outcomes of nosocomial bloodstream infections (BSIs) is of utmost importance because they are one of the most frequent and severe infectious complications of hospitalization and medical care. The outcomes of BSIs may differ depending on patient factors including underlying conditions and immune status; organism factors including virulence an...

The annual meeting of the European Society for Paediatric Infectious Diseases (ESPID) was recently held in Brussels, Belgium, and gathered world experts in pediatric infectious diseases, vaccinology, epidemiology, microbiology and public health, among others. Among nonvaccine related topics that were discussed, emphasis was given to the continuous surveillance of the most common pathogens causi...

BACKGROUND In Emergency and Medical Admission Departments (EDs and MADs), prompt recognition and appropriate infection control management of patients with Highly Infectious Diseases (HIDs, e.g. Viral Hemorrhagic Fevers and SARS) are fundamental for avoiding nosocomial outbreaks. METHODS The EuroNHID (European Network for Highly Infectious Diseases) project collected data from 41 EDs and MADs ...

Vibrio alginolyticus occasionally causes life-threatening infections in immunocompromised individuals. Bacteremia and necrotising fasciits caused by V.alginolyticus have been reported. We described a case of sepsis due to V. alginolyticus isolated from catheter of 19-year-old patient with hypercholesterolemy. Moreover the cases of invasive V.alginolyticus reported in the literature were reviewe...

Effects of methylglyoxal on human cardiac fibroblast: Roles of 1 transient receptor potential ankyrin 1 (TRPA1) channels 2 3 Gaku Oguri, Toshiaki Nakajima, Yumiko Yamamoto, Nami Takano, Tomofumi 4 Tanaka, Hironobu Kikuchi, Toshihiro Morita, Fumitaka Nakamura, Tatsuya 5 Yamasoba, Issei Komuro 6 7 1) Department of Cardiovascular Medicine, University of Tokyo, Tokyo 113-8655, 8 Japan 9 2) Departme...

Saksenaea vasiformis is an emerging human pathogen, most often associated with cutaneous or subcutaneous lesions following trauma. This is the report of a case of subcutaneous zygomycosis from which Saksenaea vasiformis was isolated on culture. As the patient developed acute interstitial nephritis, amphotericin B could not be administered in full dose. Surgical debridement was carried out, but ...

BACKGROUND In sub-Saharan Africa, community-acquired bacteraemia is an important cause of illness and death in children. Our aim was to establish the magnitude and causes of hospital-acquired (nosocomial) bacteraemia in African children. METHODS We reviewed prospectively collected surveillance data of 33,188 admissions to Kilifi District Hospital, Kenya, between April 16, 2002, and Sept 30, 2...