نتایج جستجو برای: histaminergic system

تعداد نتایج: 2231476  

2012
Xijing Zhang Hannah R. Moser Christopher N. Honda

21 22 Itch of peripheral origin requires information transfer from the spinal cord to the brain for 23 perception. Here, primate spinothalamic tract (STT) neurons from lumbar spinal cord were 24 functionally characterized using in vivo electrophysiology to determine the role of these cells in 25 the transmission of pruriceptive information. 111 STT neurons were identified by antidromic 26 stimu...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Régis Parmentier Hiroshi Ohtsu Zahia Djebbara-Hannas Jean-Louis Valatx Takehiko Watanabe Jian-Sheng Lin

The hypothesis that histaminergic neurons are involved in brain arousal is supported by many studies. However, the effects of the selective long-term abolition of histaminergic neurons on the sleep-wake cycle, indispensable in determining their functions, remain unknown. We have compared brain histamine(HA)-immunoreactivity and the cortical-EEG and sleep-wake cycle under baseline conditions or ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1991
D A McCormick A Williamson

The thalamus is innervated by histaminergic fibers presumably arising from neurons in the tuberomammillary nucleus of the hypothalamus. The possible function of this histaminergic projection was addressed through investigation of the cellular actions of histamine on guinea pig and cat dorsal lateral geniculate (LGNd) relay neurons maintained as a slice in vitro. Local application of histamine t...

Journal: :The Journal of pharmacology and experimental therapeutics 2005
Marcello Canonaco Maria Madeo Raffaella Alò Giuseppina Giusi Teresa Granata Antonio Carelli Alessia Canonaco Rosa Maria Facciolo

The neurotoxic 3-nitropropionic acid (3-NP), a freckled milk vetch-derived inhibitor of mitochondrial enzymatic processes that is capable of mimicking the typical pathological features of neurodegenerative disorders, behaved in a differentiated manner in a hibernating rodent (hamster) with respect to a nonhibernating rodent (rat). Treatment of the two rodents with both an acute and chronic 3-NP...

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