نتایج جستجو برای: hippocampal pyramidal neurons
تعداد نتایج: 204098 فیلتر نتایج به سال:
The interplay between principal cells and interneurons plays an important role in timing the activity of individual cells. We investigated the influence of single hippocampal CA1 pyramidal cells on putative interneurons. The activity of CA1 pyramidal cells was controlled intracellularly by current injection, and the activity of neighboring interneurons was recorded extracellularly in the uretha...
Animal studies have shown that prenatal stress is able to induce long-lasting neurobiological and behavioral alterations in adult offspring. In spite of the facts that hippocampus is sensitive to early developmental influences and its known functional importance in learning and memory, few data are available on the effect of prenatal stress on the structure of hippocampus. Therefore, this study...
The way hippocampal neurons function during stress in old age (critical times of life) is dependent on brain derived neurotrophin factor (BDNF). This study examined the influence of acute and chronic forced swim (FS) or high-light open field (HL‑OF) stimulation on the density of BDNF immunoreactive (ir) neurons in the hippocampal pyramidal layers of CA1, CA2, CA3 regions and the granular layer ...
A goal of many laboratories that study aging is to find a key cellular change(s) that can be manipulated and restored to a young-like state, and thus, reverse the age-related cognitive deficits. We have chosen to focus our efforts on the alteration of intrinsic excitability (as reflected by the postburst afterhyperpolarization, AHP) during the learning process in hippocampal pyramidal neurons. ...
Background and Objective: Deleterious effect of neurotoxins on the brains of animals is an attractive research topic. In this research, the effect of microinjection of colchicine into the hippocampal CA1 was shown by examining the novelty seeking behavior. Also, the effect of pre-injection of galantamine, an effective agent in the treatment and prevention of Alzheimer's disease, for reversal of...
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